The Genetic Epidemiology Branch (GEB) conducts studies to evaluate the interaction of host and environmental factors in cancer causation.
GEB's mission is to design and conduct interdisciplinary clinical, epidemiologic, genetic, and laboratory studies of persons, families, and populations at high risk of cancer.
GEB’s roots are in family studies, and a large proportion of our time and resources are still devoted to evaluation of kindreds. In addition to family studies, we conduct interdisciplinary studies in larger populations to evaluate the relevance of genetic variations in cancer etiology, where GEB investigators apply genetic and molecular epidemiologic approaches to study cancers of the lung, skin (melanoma), bone (osteosarcoma), esophagus, stomach, and breast.
Learn more about specific GEB research areas.
GEB provides an exciting and collaborative environment which offers extraordinary opportunities for young scientists embarking on research careers. Meet the current GEB fellows and learn about research training opportunities in GEB.
A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma. Cancer Discov 2015; Mirabello L, et al.
Time to smoke first morning cigarette and lung cancer in a case-control study. J Natl Cancer Inst 2014; Gu F, et al.
Female breast cancer incidence among Asian and Western populations: more similar than expected. J Natl Cancer Inst 2015; Sung H, Yang XR, et al.
Lung cancer prognosis before and after recurrence in a population-based setting. J Natl Cancer Inst 2015; Landi MT, Goldstein A, Goldin LR, Caporaso NE, et al.
Genome-wide association study of gastric adenocarcinoma in Asia: a comparison of associations between cardia and non-cardia tumours. Gut 2015; Hu N, Wang Z, Goldstein AM, Taylor PR, et al.
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma. Nat Gen 2014;Yang XR, Rotunno M, Goldin L, Goldstein A, Landi MT, et al.