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Discovering the causes of cancer and the means of prevention

Chief, Laboratory of Translational Genomics

The Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH) ( is recruiting a senior scientist to serve as Chief of the Laboratory of Translational Genomics (LTG). LTG's mission is to understand the contribution of germline and somatic genetic variation to cancer etiology and outcomes ( The LTG conducts focused studies on particular regions of the genome conclusively identified in cancer-specific genome-wide association studies (GWAS), next-generation sequencing (NGS), and linkage studies in high-risk families. Its primary goals are to investigate regions of genetic variation by detecting cancer susceptibility alleles; carrying out fine mapping of susceptibility alleles using sequence analysis and imputation from public databases; deciphering the biological mechanisms underlying susceptibility alleles through laboratory investigation; prioritizing variants for prognostic or risk prediction markers through bioinformatic analysis; and exploring their potential for clinical application.

The Laboratory Chief will have the opportunity and resources to conduct an independent program of research and to shape the research direction of LTG.  The Laboratory currently includes a staff of 3 tenure-track investigators as well as pre- and post-doctoral fellows and a staff scientist; additional recruitments are anticipated. LTG also maintains close analytical, laboratory, and technical ties with DCEG’s Cancer Genomic Research Laboratory (, a state-of-the-art facility that provides high-quality genetic data along with analytical expertise in quality control assessment, primary analyses of molecular epidemiology studies, and methods development.

The successful candidate must hold either a medical degree or other biomedical doctoral degree in genetics, genomics, or related fields.  He or she must demonstrate experience in managing and directing a relevant laboratory program and have extensive familiarity with large-scale genome-wide association/linkage studies and/or NGS, and follow-up translational germline and somatic analyses. In addition, he or she must have a proven ability to: (1) conduct high-quality original research to investigate the role of genetic susceptibility to cancer; and (2) publish such work in peer-reviewed scientific or medical journals and present it at scientific meetings. The candidate must also demonstrate communication skills and management experience as a senior level scientific administrator who has led teams of investigators involved in conducting a broad range of interdisciplinary cancer genetics studies.

The Chief, Laboratory of Translational Genomics will be eligible for a tenured appointment at a salary commensurate with his/her qualifications and experience.  Full Federal benefits including leave, health and life insurance, long-term care insurance, retirement, and savings plan (401k equivalent) will be provided.

Interested individuals should send a cover letter, curriculum vitae and bibliography, a brief summary of research interests and accomplishments, scientific administrative experience, copies of up to five publications or preprints, and the names and addresses of three references to:

Ms. Catherine McClave
Division of Cancer Epidemiology and Genetics, National Cancer Institute
9609 Medical Center Drive, Rm. 7E-440
Bethesda, MD 20892-9774

Applications received by January 31, 2014 will be considered for a first round of interviews, but applications will be accepted until the position is filled.

The DHHS and the NIH are Equal Opportunity Employers.