Biography
Dr. Pfeiffer was the recipient of a Fulbright Fellowship to study applied statistics in 1992-1993, and received a Ph.D. in mathematical statistics from the University of Maryland, College Park, in 1998. She joined NCI in 1999 as a CRTA fellow. She was appointed as a principal investigator in 2001 and was tenured as a senior investigator in February 2007. Her research focuses on statistical methods for laboratory methods and problems arising in genetic epidemiology.
Research Interests
- Statistical methods for family data accounting for ascertainment
- Mixture models and applications
- Methods for analysis of high dimensional data
- Absolute risk modeling
- Power considerations for association studies
Keywords
genetic epidemiology; ascertainment; family studies; DNA pooling; familial aggregation; mixture models; random effects models; laboratory methods; association studies; absolute risk modeling.
Selected Publications
- Pfeiffer RM, Forzani L, Bura E. Sufficient dimension reduction for longitudinally measured predictors. In Press
- Pfeiffer RM, Gail MH. Two criteria for evaluating risk prediction methods. Biometrics 2011; 67:1057-65.
- Pfeiffer R, Petracci E. Variance computations for functionals of absolute risk estimates. Statistics & Probablility Letters 2011; 81:807-12.
- Pfeiffer RM, Wheeler WA, Mbisa G, Whitby D, Goedert JJ, de The G, Mbulaiteye SM. Geographic heterogeneity of prevalence of the human herpesvirus 8 in sub-Saharan Africa: clues about etiology. Ann Epidemiol 2010; 20:958-963.
- Pfeiffer RM, Gail MH, Pee D. On Combining data from Genome-Wide Association Studies to discover disease-associated SNPs. Statistical Science 2009; 24:547-560.
- Pfeiffer RM, Pee D, Landi MT. On combining family and case-control studies. Genetic Epidemiology 2008; 32:638-46
- Pfeiffer RM, Carroll RJ, Wheeler W, Whitby D, Mbulaiteye S. Combining assays for estimating prevalence of human herpesvirus 8 infection using multivariate mixture models. Biostatistics 2008; 9:137-51.
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