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Discovering the causes of cancer and the means of prevention

2011 Radiation Epidemiology and Dosimetry Course

Welcome to the 2011 Radiation Epidemiology and Dosimetry Course, conducted by NCI’s Division of Cancer Epidemiology and Genetics (DCEG). This course is intended for people with backgrounds in epidemiology who are interested in learning about the health effects of radiation exposure–particularly the relationship between ionizing radiation and cancer. We’ve designed the course assuming that you are familiar with basic epidemiologic concepts, terminology and methods of data analysis, but we intend that most of the material will be understandable by people with college-level training in basic biology, chemistry and physics.

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To view the course lecture videos, simply click on the names of the presentations listed below.

Day 1, May 17, 2011 – Morning Session

Welcome, Introduction, and Overview (5 min.) Alice Sigurdson, Ph.D.
Basic Epidemiology Concepts and Study Design (55 min.) Martha Linet, M.D., M.P.H.
Radiation Risk Modeling (105 min.) Ethel Gilbert, Ph.D.

Day 1, Tuesday May 17, 2011–Afternoon Session

Principles of Radiation Physics and Dosimetry: External and Internal Exposures (120 min.) Steve Simon, Ph.D.
Classic External Radiation Studies and Concepts (105 min.) John Boice, Sc.D.

Day 2: Wednesday May 18, 2011–Morning Session

Radiation Chemistry and Biology

Radiation Chemistry and the Chemistry Underlying DNA Damage (70 min.)
Radiobiology for the Radiation Epidemiologist (60 min.)
Biodosimetry to Measure Long-term Low-dose Radiation Exposure in the Past (60 min.)

John Ward, Ph.D.

David Brenner, Ph.D.
James Tucker, Ph.D.

Day 2: Wednesday May 18, 2011–Afternoon Session

DNA Damage and Genetic Susceptibility to Radiation

Cellular Defenses Against Radiation-Induced Damage: Cell Cycle Arrest, DNA Repair and Apoptosis (60 min.)
Phenotypic Markers of Radiation Sensitivity (60 min.)
Germline Polymorphic Variation, Radiation and Cancer Susceptibility (45 min.)
Statistical Methods in the Search for Gene-Radiation Interaction (60 min.)

William Morgan, Ph.D., D.Sc.

William Morgan, Ph.D., D.Sc.
Preetha Rajaraman, Ph.D.

Daniel Stram, Ph.D.

Day 3: Thursday, May 19, 2011–Morning Session

Studies of Irradiated Populations: Environmental and Occupational Studies

Atomic Bomb Survivors (90 min.)
Radon: Underground Miners and Residential Exposure (45 min.)
Radiation Workers(45 min.)
Radiation Risk Assessment(45 min.)
Dosimetry Uncertainties(40 min.)
Complex Statistical Approaches and Uncertainties(35 min.)

Dale Preston, Ph.D.
Jay Lubin, Ph.D.

Ethel Gilbert, Ph.D.
Amy Berrington de González, D.Phil.
André Bouville, Ph.D.
Mark Little, Ph.D.

Day 3: Thursday, May 19, 2011–Afternoon Session

Nuclear Incidents and Accidents (including Fukushima)

Introduction to Nuclear Incidents (30 min.)
Nuclear Reactor Accidents (Three Mile Island, Chernobyl), Dosimetry and Health Effects (60 min.)
Acute Biologic Dosimetry (30 min.)
Emergency Response and Countermeasures (30 min.)
Afternoon Panel: Questions and Comments (30 min.)

Steve Simon, Ph.D.
Vladimir Drozdovitch, Ph.D.,
Maureen Hatch, Ph.D.
William Blakely, Ph.D.
Albert Wiley, M.D., Ph.D.
Kiyo Mabuchi, M.D.,Dr.P.H. (moderator)

Day 4: Friday, May 20, 2011–Morning Session

Studies in Medically Irradiated Populations: Diagnostic Procedures and Therapy

Radiation Dosimetry and Organ Doses from Imaging (45 min.)
Diagnostic Imaging, Screening and Cancer Risk (45 min.)
Radiation Dosimetry from Treatment (60 min.)
Cancer Risk in Adults Undergoing Radiotherapy (45 min.)
Cancer Risk in Children Undergoing Radiotherapy (45 min.)
Internally Administered Radionuclides (I-131): Dosimetry and Health Effects (45 min.)
Non-cancer Outcomes from Radiation Exposure (45 min.)

Choonsik Lee, Ph.D.

Amy Berrington de González, D.Phil.
Rebecca Howell, Ph.D.
Lindsay Morton, Ph.D.
Peter Inskip, Sc.D.

Steve Simon, Ph.D., Alina Brenner, M.D., Ph.D.
Kiyo Mabuchi, M.D., Dr.P.H.

Day 4: Friday, May 20, 2011–Afternoon Session

Non-Ionizing Radiation

Electromagnetic Fields (30 min.)
UV Radiation: Risk and Protective Effects (30 min.)
Course Wrap-up and Evaluation (5 min.)

Martha Linet, M.D., M.P.H.
Michal Freedman, M.P.H., Ph.D.
Alice Sigurdson, Ph.D.

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