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Discovering the causes of cancer and the means of prevention

2011 Radiation Epidemiology Course Handouts

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Day 1 - May 17, 2011

Welcome, Introduction, and Overview Alice Sigurdson, Ph.D.
Basic Epidemiology Concepts and Study Design Martha Linet, M.D., M.P.H.
Radiation Risk Modeling Ethel Gilbert, Ph.D.
Principles of Radiation Physics and Dosimetry: External and Internal Exposures Steve Simon, Ph.D.
Classic External Radiation Studies and Concepts John Boice, Sc.D.

Day 2 - May 18, 2011

Radiation Chemistry and Biology

Radiation Chemistry and the Chemistry Underlying DNA Damage
Radiobiology for the Radiation Epidemiologist
Biodosimetry to Measure Long-term Low-dose Radiation Exposure in the Past

John Ward, Ph.D.

David Brenner, Ph.D.
James Tucker, Ph.D.

DNA Damage and Genetic Susceptibility to Radiation

Cellular Defenses Against Radiation-Induced Damage: Cell Cycle Arrest, DNA Repair and Apoptosis
Phenotypic Markers of Radiation Sensitivity
Germline Polymorphic Variation, Radiation and Cancer Susceptibility
Statistical Methods in the Search for Gene-Radiation Interaction

William Morgan, Ph.D., D.Sc.

William Morgan, Ph.D., D.Sc.
Preetha Rajaraman, Ph.D.

Daniel Stram, Ph.D.

Day 3 - May 19, 2011

Studies of Irradiated Populations: Environmental and Occupational Studies

Atomic Bomb Survivors
Radon: Underground Miners and Residential Exposure
Radiation Workers
Radiation Risk Assessment
Dosimetry Uncertainties
Complex Statistical Approaches and Uncertainties

Dale Preston, Ph.D.
Jay Lubin, Ph.D.
Ethel Gilbert, Ph.D.
Amy Berrington de González, D.Phil.
André Bouville, Ph.D.
Mark Little, Ph.D.

Nuclear Incidents and Accidents (including Fukushima)

Introduction to Nuclear Incidents
Nuclear Reactor Accidents (Three Mile Island, Chernobyl),Dosimetry and Health Effects
Acute Biologic Dosimetry
Emergency Response and Countermeasures
Afternoon Panel: Questions and Comments

Steve Simon, Ph.D.
Maureen Hatch, Ph.D.,
Vladimir Drozdovitch, Ph.D.
William Blakely, Ph.D.
Albert Wiley, M.D., Ph.D.
Kiyo Mabuchi, M.D.,Dr.P.H. (moderator)

Day 4 - May 20, 2011

Studies in Medically Irradiated Populations: Diagnostic Procedures and Therapy

Radiation Dosimetry and Organ Doses from Imaging
Diagnostic Imaging, Screening and Cancer Risk
Radiation Dosimetry from Treatment
Cancer Risk in Adults Undergoing Radiotherapy
Cancer Risk in Children Undergoing Radiotherapy
Internally Administered Radionuclides (I-131): Dosimetry and Health Effects
Non-cancer Outcomes from Radiation Exposure

Choonsik Lee, Ph.D.
Amy Berrington de González, D.Phil.
Rebecca Howell, Ph.D.
Lindsay Morton, Ph.D.
Peter Inskip, Sc.D.
Steve Simon, Ph.D.
Kiyo Mabuchi, M.D., Dr.P.H.

Non-Ionizing Radiation

Electromagnetic Fields
UV Radiation: Risk and Protective Effects
Course Wrap-up and Evaluation

Martha Linet, M.D., M.P.H.
Michal Freedman, M.P.H., Ph.D.
Alice Sigurdson, Ph.D.