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July 2013 Linkage Newsletter

Table of Contents

Research & Publications

News & Events

DCEG Staff Updates

Fellowship News

Scientific Highlights 

Risk Prediction Based on Polygenic Models

The authors report a new method to estimate the predictive performance of polygenic models for risk prediction.

Body Mass Index, Physical Activity, and Endometrial Cancer Survival

Higher prediagnosis body mass index increased the risk of five- and ten-year overall and disease-specific mortality among women diagnosed with endometrial cancer, whereas physical activity lowered the risk in the NIH-AARP Diet and Health Study.

Telomere Length, TERT, and Lung Cancer

A nested case-control study of lung cancer among mostly never-smoking women in China showed a dose-response relationship between lymphocyte telomere length and risk of lung cancer and the rs2736100 G allele in the TERT-CLPTM1L locus on chromosome 5p15.33.

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