Skip to Content
Discovering the causes of cancer and the means of prevention

Information for Journalists

To request an interview with a DCEG investigator, contact the NCI Office of Media Relations:


Phone: 301-496-6641

Study finds stronger nicotine dependency associated with higher risk of lung cancer

Posted on June 19, 2014

People who are highly addicted to nicotine -- those who smoke their first cigarette within five minutes after awakening -- are at higher risk of developing lung cancer than those who wait for an hour or more to smoke. Researchers at NCI found this simple measure of nicotine dependency improved lung cancer risk prediction beyond standard smoking measures, such as cigarettes per day, age, gender, history of chronic obstructive pulmonary disease and other lung cancer risk factors. The results of this study were published online in the Journal of the National Cancer Institute, June 19, 2014. Read more in the full NCI News Note.

Reference: Gu F, Wacholder S, Kovalchik S, Panagiotou OA, et al. Time to smoke first morning cigarette and lung cancer in a case-control study. J Natl Cancer Inst. 2014; 106:dju118.

Related Links

DCEG research on lung cancer

Biography of Fangyi Gu, M.Med., Sc.D.

Biography of Neil E. Caporaso, M.D.