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July 2009 • Number 36
   

DCEG Participates in the 100th Annual AACR Meeting

In April, many DCEG members attended the 100th Annual Meeting of the American Association for Cancer Research (AACR) in Denver. This event brought together researchers from around the world to highlight the most prominent advances in understanding cancer etiology, treatment, and prevention. Joseph F. Fraumeni, Jr., M.D., Division Director, received the AACR Award for Lifetime Achievement in Cancer Research (see back cover).

More than 30 posters involving DCEG researchers were chosen for presentation. Several posters were highly rated, a designation for an abstract scoring in the top 3 to 4 percent of posters presented; a few also received awards or recognition by the press. Occupational and Environmental Epidemiology Branch (OEEB) investigators Linda Dong, Ph.D., and Min Shen, M.D., Ph.D., won AACR-Aflac Scholar-in-Training Awards for their highly rated posters “Urinary prostaglandin E2 metabolite and gastric cancer risk in the Shanghai Women’s Health Study” and “A prospective study of telomere length and risk of lung cancer,” respectively. Other researchers with highly rated posters included H. Dean Hosgood, III, Ph.D. (OEEB), “Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study”; Maria Teresa Landi, M.D., Ph.D., Genetic Epidemiology Branch (GEB), “MicroRNA expression, tobacco smoking, and genetic polymorphisms in lung cancer histology and survival”; Lee E. Moore, Ph.D. (OEEB), “VHL gene alteration and histopathologic risk factors in a large renal cancer case-control study”; Mark Purdue, Ph.D. (OEEB), “A prospective study of serum soluble CD30 concentration and risk of non-Hodgkin lymphoma”; and Huei-Ting Tsai, Ph.D. (GEB), “Evidence of immune disruption up to 9.8 years prior to diagnosis of chronic lymphocytic leukemia: A prospective study,” which was presented at a press conference by Neil E. Caporaso, M.D. (GEB).

Stephen J. Chanock, M.D., Director of the Core Genotyping Facility and Chief of the Laboratory of Translational Genomics (LTG), cochaired the symposium “Genome-wide association studies (GWAS) in cancer: Current and future directions” and presented “Discovery of new loci in GWAS of common cancers.” Montserrat García-Closas, M.D., Dr.P.H., Hormonal and Reproductive Epidemiology Branch (HREB), chaired and introduced the symposium “Development and characterization of biomarkers for epidemiological studies.” 

Other DCEG presenters included Laufey Amundadottir, Ph.D. (LTG), “Genetic risk factors for pancreatic cancer from genome-wide association studies”; Eric A. Engels, M.D., M.P.H., Infections and Immunoepidemiology Branch, “Viruses, immunity, and cancer”; Ann W. Hsing, Ph.D. (HREB), “High prevalence of screen-detected prostate cancer in West Africans: Implications for racial disparity of prostate cancer”; Mitchell H. Gail, M.D., Ph.D., Biostatistics Branch, “The value for clinical and public health decisions of adding single nucleotide polymorphisms to a model to project breast cancer risk”; and Nathaniel Rothman, M.D., M.P.H., M.H.S. (OEEB), “Principles of biomarker characterization for epidemiological studies” and “Environmental and occupational cancer research in the age of genomics.”

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