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Investigating the causes of cancer through population-, family-, and lab-based research

Research & Publications

Cohort Consortium Studies Obesity

In many developed countries today, more than half the population is overweight or obese, and the potential impact of this situation on total mortality has drawn considerable attention.

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News & Events

DCEG Training Program Receives Langmuir Award

In June, DCEG received the inaugural Alexander D. Langmuir Award for Training Program Excellence and Innovation.

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Inside DCEG

Mark Purdue Profile

According to Mark Purdue, Ph.D., a tenure-track investigator in the Occupational and Environmental Epidemiology Branch (OEEB), "My interest is in combining environmental epidemiology with molecular techniques to study the causes of cancer…"

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Fellowship News

Third Annual DCEG Fellows' Training Symposium

March 2011 marked the third annual DCEG Fellows' Training Symposium, titled Shaping Future Research: Provocative Questions in Cancer Epidemiology and Genetics.

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Distinguished Visiting Scholars

DCEG regularly brings world-class scientists in the field of cancer epidemiology and genetics to NCI to share their expertise with scientific staff through special seminars, small meetings, and informal lunch discussions.

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Obesity: A Provocative Question and the Search for Answers

NCI Director Harold Varmus, M.D., created the "Provocative Questions" initiative to assemble a list of important topics and advances that will stimulate NCI's research communities to use laboratory, clinical, and population sciences in effective and imaginative ways. One question particularly resonates for DCEG investigators: What molecular mechanisms underlie the association of obesity with the risks of cancer?

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Applied Molecular Pathology Lab

Large-scale analyses of tumor tissue samples can contribute greatly both to molecular epidemiologic investigations aimed at defining the causes of cancer and the mechanisms that mediate them as well as to translational studies that seek to apply this knowledge to improve public health or clinical management.

The Applied Molecular Pathology Laboratory (AMPL), an interdisciplinary effort initiated in 2009 and funded jointly by DCEG and the Center for Cancer Research (CCR), is a high-throughput lab that designs and constructs tissue microarrays (TMAs) and develops and implements other promising tissue-based molecular assays in a validated, standardized fashion. It was developed to apply standardized testing to thousands of tissue specimens concurrently in support of large intramural studies in DCEG and CCR. Read the full story >

Elaine Ron Memorial Symposium

Elaine Ron, Ph.D., former Chief and senior investigator, Radiation Epidemiology Branch (REB), was honored posthumously at a symposium titled "Research Strategies in Radiation and Cancer" on March 9. An international leader in the field of radiation epidemiology, Dr. Ron died of cancer on November 20, 2010.

Joseph F. Fraumeni, Jr., M.D., DCEG Director, provided the opening remarks, noting that "Elaine was an enormously gifted epidemiologist whose groundbreaking research has contributed so much to a better understanding of the risks of cancer associated with a wide variety of exposures to ionizing radiation." Martha S. Linet, M.D., M.P.H., Chief of REB, also offered remarks on the life and legacy of Dr. Ron, highlighting the progression of her research over the years. Read the full story >