DCEG researchers conduct studies on Kaposi sarcoma (KS). Infection with KS-associated herpesvirus (KSHV, also known as human herpesvirus-8 [HHV-8]) is necessary for KS to occur, but other factors, such as HIV infection, greatly increase the risk of the disease. Selected studies include:
A population-based case-control study in Sicily investigating the effects of various factors on the risk of Kaposi sarcoma-associated herpesvirus infection and classical Kaposi sarcoma
Studies of Kaposi sarcoma-associated herpesvirus transmission and prevalence in Uganda
Studies that address unresolved questions on the genomic integrity of Kaposi sarcoma (KS) and whether multiple tumors in individuals are clonal