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Kaposi Sarcoma Molecular Studies

Investigators in DCEG are addressing unresolved questions on the genomic integrity of Kaposi sarcoma (KS) and whether multiple tumors in individuals are clonal. Identifying clonal abnormalities in tumors would confirm its malignant nature and clarify its pathogenesis. To determine genomic integrity (loss or gain of gene regions) and clonality of KS, investigators will complete analyses using digital comparative genomic hybridization and other clonal markers to compare multiple tumors with each other and with normal skin from Ugandan subjects with AIDS-related and endemic KS. 

For more information, contact Sam Mbulaiteye.

Infections and Immunoepidemiology Branch – Research Areas