A family study is currently ongoing in Taiwan to elucidate genetic factors linked to the development of nasopharyngeal cancer (NPC). Approximately 150 multiplex families with two or more individuals affected with NPC have been identified and are being recruited into the study. Genome-wide genetic screening is planned followed by analyses to identify chromosomal regions that may be linked to NPC. Candidate polymorphic genes (HLA, CYP2E1, and others) are also being tested. A risk factor questionnaire is administered to all participants to allow us to examine the joint effects of genetic and environmental factors in the pathogenesis of NPC.
For more information, contact Allan Hildesheim.