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UGCRG Selected Ongoing Projects

The UGI Cancer Research Group is currently conducting projects in the United States and in several high-risk areas of the world, including China, Iran, Brazil, Kenya and Poland. Some of these projects are:
  • Planning a community-based selenium fortification trial in an area at high risk for esophageal and gastric cancer
  • The GEMINI case-control study of esophageal cancer in Golestan Province, Iran
  • The Golestan Cohort Study of esophageal cancer in Golestan Province, Iran
  • Evaluation of HPV as a causative agent for esophageal squamous cell carcinoma
  • Evaluation of oral bacteria as a risk factor for UGI cancers
  • Evaluation of gastric atrophy as a risk factor for UGI cancers
  • Searching for new viruses associated with UGI cancers
  • PAH exposure as a risk factor for UGI cancers
  • Acetaldehyde exposure as a risk factor for UGI cancers
  • Using gene methylation profiles or gene copy number variation for early detection of ESCC
  • Developing a serum autoantibody test for early detection of ESCC
  • Development of molecular markers for early detection of Barrett esophagus