Skip to Content

HIV/AIDS Cancer Match, U.S.

The HIV/AIDS Cancer Match Study is designed to examine cancer risk in people living with HIV infection in the United States. The study utilizes data collected by state and regional HIV/AIDS and cancer registries throughout the United States. The NCI uses these study data to determine the spectrum of cancers that occur in HIV-infected people. The risk of cancer in HIV-infected people is compared with that in the general population to determine which cancers arise more frequently than expected. Investigators compare different groups of HIV-infected people to determine whether certain individuals are at especially high risk of cancer. Through frequent updates of the data, investigators also monitor changing trends in cancer risk over time.

People who are infected with the HIV or who have AIDS have an elevated risk for some cancers. This high risk occurs because HIV weakens the immune system, and because many other cancer risk factors are common in HIV-infected people. By studying the patterns of cancer risk among HIV-infected people, DCEG investigators seek to better understand how the immune system protects people from developing cancer. Another goal of the study is to look for trends in cancer risk in the HIV populations and identify important opportunities for cancer prevention.

For more information, contact Eric Engels.

Infections and Immunoepidemiology Branch – Research Areas