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Discovering the causes of cancer and the means of prevention

Genes/ Host

DCEG researchers investigate genetic and/or host factors – characteristics by which individuals are predisposed to cancer. 

Endogenous Hormones

Investigations into how the body’s own hormone production may be related to risk for breast, endometrial, and ovarian cancer as well as testicular cancer and other malignancies. Learn more about DCEG research on endogenous hormones.

Genetic and Molecular Studies in Radiation

Studies to understand the interplay of molecular and genetic effects and radiation on cancer etiology. This type of work involves biological samples and high-quality dosimetry or other exposure assessment. Learn more about DCEG genetic and molecular studies in radiation.

Genetic Susceptibility

Studies of the role of common and uncommon inherited variations in the genetic code that are associated with increased risk of cancer. Learn more about DCEG research on genetic susceptibility.

Hereditary Cancer Syndromes

Studies of a range of inherited syndromes that may predispose affected individuals and their family members to cancer. Learn more about DCEG research on hereditary cancer syndromes.

Immunologic Factors

Studies of the role of the immune system in cancer etiology, measuring the immune response as part of the host response to exogenous (outside) exposures, and considering how chronic inflammation from infection is related to cancer risk. Learn more about DCEG research on immunologic factors.

Reproductive Factors

Studies of how parity, infertility, age at menarche and menopause and other factors influence risk of hormone-related cancers. Learn more about DCEG research on reproductive factors.

Telomere Molecular Epidemiology

Studies of nucleoprotein structures that are designed to protect the ends of chromosomes and are critical to chromosome stability. Research covers characterization of telomere length as a cancer risk factor and identification of genetic determinants of telomere length. Learn more about DCEG research on telomere molecular epidemiology.