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Tobacco use is well understood to be a risk factor for cancer. Although smoking rates in the United States have declined, tobacco continues to exert a tremendous burden on the health of populations in the U.S. and world-wide. Investigators throughout DCEG have used case-control, prospective studies, and consortia to characterize changing associations between cigarette smoking and cancer, and are engaged in determining the health risks of other tobacco and tobacco-related products, including smokeless tobacco, flavored cigarillos, electronic cigarettes, and hookah (water pipe). 

Search for DCEG publications on tobacco use and cancer.

Examples of studies used in these investigations include:

Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
Prostate, Lung, Colon, and Ovary Prospective Study
NIH-AARP Diet and Health Study
Environment And Genes in Lung cancer Etiology (EAGLE)

Barrett’s and Esophageal Adenocarcinoma Consortium (BEACON)
Case-Control Study of Biliary Tract Cancer in Shanghai

Case-Control Studies of Cancers of the Digestive Tract in Shanghai

Gastric and Esophageal Malignancies in Northern Iran (GEMINI)
Golestan Cohort Study

U.S. Radiologic Technologists Cohort
New England Bladder Cancer Study
Interdisciplinary Case-Control Study of Bladder Cancer in Spain
Case-Control Studies of Stomach Cancer in the United States, Poland, and Mexico
Case-Control Studies of Multiple Myeloma and Cancers of the Pancreas and Prostate among Blacks and Whites in the United States