Tobacco use is well understood to be a risk factor for cancer. Although smoking rates in the United States have declined, tobacco continues to exert a tremendous burden on the health of populations in the U.S. and world-wide. DCEG has a long-standing interest in the associations between tobacco and cancer. Investigators throughout the Division use case-control, prospective studies, and consortia to characterize changing associations between cigarette smoking and cancer. They are also committed to determining the health risks of other tobacco products, including smokeless tobacco, pipes, cigars, as well as new and emerging products such as water pipe. Search for DCEG publications on tobacco use and cancer.
Examples of studies include:
A study conducted in Finland to evaluate the long-term effects of vitamins on cancer incidence (lung and other cancers), and on overall and cause-specific mortality
A large cohort study of etiologic determinants of cancer carried out within an NCI trial for the evaluation of screening procedures for the early detection of prostate, lung, colon, and ovarian cancer (the PLCO Trial) at 10 U.S. screening centers
A study developed at NCI to improve our understanding of the relationship between diet and health
A large population-based case-control study designed to investigate the genetic and environmental determinants of lung cancer and smoking persistence
An international consortium with epidemiologic studies of esophageal adenocarcinoma and Barrett's esophagus
A population-based case-control study investigating risk factors for biliary tract cancer in Shanghai, China
DCEG population-based case-control studies of cancers of the digestive tract in Shanghai, China
A case-control study evaluating environmental and genetic risk factors for esophageal squamous cell carcinoma in Golestan Province, Iran
A cohort study evaluating the environmental and genetic risk factors for esophageal squamous cell carcinoma in Iran
A study of a number of different lifestyle factors in relation to various morbidity and mortality outcomes among the U.S. Radiologic Technologists.
A population-based case-control study that investigates the reason for the persistent excess of bladder cancer mortality and incidence in the northern New England area.
A large interdisciplinary case-control study of bladder cancer in 18 hospitals from five different regions in Spain
Case-control studies of stomach cancer in the United States, Poland, and Mexico
DCEG case-control studies of multiple myeloma and cancers of the pancreas and prostate among blacks and whites in the United States