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Contralateral Breast Cancer

Breast cancer survivors constitute about 25% of the growing population of cancer survivors in the US. Contralateral breast cancer is the most common second cancer in women with primary breast cancer. With increasing cure rates comes increasing concern about their long-term health. Radiation Epidemiology Branch (REB) investigators and collaborators from the Kaiser health maintenance organization have developed a retrospective cohort of about 7,000 breast cancer patients diagnosed since 1991. By linking electronic treatment files and the Kaiser cancer registries for information on subsequent cancers, researchers have developed a rich resource for studying the late effects of breast cancer treatments. Tumor tissue samples from both the first and second breast cancers and mammography films have also been collected. Analyses are underway to evaluate the relationship among radiotherapy, newer hormonal therapies, chemotherapy agents, and obesity in survivors.

For more information, contact Amy Berrington de González.