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Case-Control Studies of Multiple Myeloma and Cancers of the Pancreas and Prostate among Blacks and Whites in the United States

U.S. blacks are at greater risk for these diseases than whites. The NCI and collaborators in New Jersey, Detroit, and Atlanta carried out a large-scale investigation to identify risk factors for these diseases among blacks and whites resident in these areas. Data have been collected from more than 2,000 cases (multiple myeloma, 587; pancreas 527; prostate, 1,000) and 2,100 controls approximately equally divided between blacks and whites. Investigators have studied the role of antigenic stimulation in the etiology of multiple myeloma, tobacco and alcohol use and family history in the etiology of prostate cancer, and tobacco and alcohol use in the etiology of pancreatic cancer. Efforts continue to evaluate other potential risk factors, including dietary and nutritional factors, viruses, medical conditions, socioeconomic status, and occupational exposures.

For more information, contact Debra Silverman.

Occupational and Environmental Epidemiology Branch - Research Areas