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Genetic Epidemiology of Cancer Postdoctoral Fellowship

Work with Dr. Mitchell Machiela

Mitchell Machiela, Sc.D., M.P.H.

Dr. Mitchell Machiela, an investigator in the DCEG Integrative Tumor Epidemiology Branch, is seeking a postdoctoral fellow with interest in conducting integrative analyses on the genetic etiology of cancer. Genetic epidemiology has remarkable potential to improve understanding of cancer etiology by identifying germline genetic variation and acquired somatic mutations associated with cancer risk. Specific areas of Dr. Machiela's research include:

  1. Next-generation sequencing studies to identify acquired mutations that could impact cancer risk in special exposure populations (e.g., drug and radiation exposure);
  2. Studies characterizing the distribution and determinants of structural mosaic copy number changes in large cancer case/control and cohort studies (~200,000 participants) with existing array genotyping data; and
  3. Genome-wide association studies (GWAS) in pediatric cancers to identify and functionally map germline variants associated with increased risk (e.g., Ewing sarcoma).

All studies of the genetic etiology of cancer are population-based with extensive data on exposures, genetic variation and phenotypic characterization. 

Learn more about the advantages of being a DCEG fellow, including our distinctive research environment, mentorship, professional development, compensation and benefits, and commitment to diversity and inclusion.


The potential candidate will be part of an interdisciplinary team of genetic, bioinformatic and laboratory investigators. The NCI’s Division of Cancer Epidemiology (DCEG) has a long tradition of carrying out large-scale, state-of-the-art population studies and has excellent computing resources for next-generation sequencing and genetic epidemiologic analyses. In addition, DCEG offers extensive career development training through its Office of Education.


Applicants with a doctoral degree in genetic epidemiology, genetics/genomics, statistical genetics or related field, are encouraged to apply. Experience in analyses of large complex genomic datasets, next-generation sequencing, GWAS, and/or bioinformatic methods is a plus. A successful candidate will have excellent written and verbal communication skills, be self-motivated and able to work in a multidisciplinary team. Salary and benefits are highly competitive and commensurate with experience.


Submit your CV to the application database so it can be reviewed by investigators across the Division searching for trainees. Review of applications will continue until the position is filled. Applicants may be U.S. citizens, permanent residents; or foreign nationals (visa requirements apply). Candidates are subject to a background investigation.

For more information about this position, please contact Mitchell Machiela, Sc.D., M.P.H., Earl Stadtman Investigator.

To explore other integrative tumor epidemiology fellowships, see the Integrative Tumor Epidemiology Fellowships Opportunities page. 

DHHS, NIH, and NCI are Equal Opportunity Employers and dedicated to building a diverse community in their training and employment programs.

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