NCI Shady Grove, Joseph F. Fraumeni, M.D., Conference Room, TE406
Description: A day-long symposium hosted by the NCI Division of Cancer Epidemiology and Genetics (DCEG) in celebration of the 10th anniversary of the founding of the Laboratory of Translational Genomics (LTG). LTG investigators will present their most notable findings and discuss the future of the LTG and the field.
The mission of the LTG is to understand the contribution of germline and somatic genetic variation to cancer etiology and outcomes. This was a fruitful decade for the LTG, with scores of discoveries based on GWAS findings for multiple cancers coming from the Cancer Genomics Research Laboratory/DCEG pipeline.
This event is open to all NCI staff.
9.00 - 9.20: Opening remarks by Stephen Chanock, DCEG Director and Ludmila Prokunina-Olsson, LTG Acting Chief
9.20 - 9.45: Laufey Amundadottir, Senior Investigator, “Making Sense of Genome-Wide Association Studies for Pancreatic Cancer Risk”
9.45 – 10.00: Jason Hoskins, Staff Scientist, “A Network-Based Approach to GWAS Interpretation”
10.00 - 10.35: Melissa Troester, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, “Predictive Biomarkers in Benign Breast and Breast Cancer”
10.35 - 10.50: Break
10.50 - 11.15: Kevin Brown, Senior Investigator, “Familial and Population Risk Loci Predisposing to Melanoma”
11.15 – 11.30: Jiyeon Choi, Research Fellow, “SNP to Animal Model: Fast-Tracking GWAS Annotation with High-Throughput Screening and eQTLs”
11.30 - 11.55: Michael Dean, Senior Investigator, “Genetic Analyses of Cervical Cancer and Human Papilloma Viruses”
11.55 – 13.00: Lunch on your own
13.00 - 13.15: Leandro Colli, Post-Doctoral Fellow, “High Throughput Post-GWAS Approach Identified a New SWI/SNF Complex Member Involved on RCC Oncogenesis: from Apoptosis to Potential Immunotherapy Response”
13.15 - 13.50: Katherine Nathanson, Perelman School of Medicine, University of Pennsylvania, “From Soup to Nuts: Inherited Genetics and Testicular Germ Cell Tumors”
13.50 - 14.15: Ludmila Prokunina-Olsson, Acting Chief, “The Translatable Genomics”
14.15 - 14.30: Rouf Banday, Research Fellow, “Genetic and Environmental Regulation of APOBEC Mutagenesis”
14.30 - 15.05, Robert Klein, Icahn School of Medicine at Mount Sinai, New York, “Using eQTL Networks to Understand Prostate Cancer Risk Loci”
15.05 - 15.20: Break
15.20 - 16.20: Panel discussion about future of translational research moderated by Sharon Savage, Chief, Clinical Genetics Branch and Clinical Director
16.20 - 17.00: Closing remarks
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