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Discovering the causes of cancer and the means of prevention

Dean Named Chief of DCEG Laboratory of Translational Genomics

Michael Dean

Michael Dean, Ph.D., has been appointed Chief of the DCEG Laboratory of Translational Genomics. Dr. Dean takes over from Margaret Tucker, M.D., who has generously served as Acting Chief for LTG for almost two years.

Dr. Dean was most recently senior investigator and Head of the Human Genetics Section in the Laboratory of Experimental Immunology, and Deputy Director of the Cancer and Inflammation Program in the NCI Center for Cancer Research. Using exome sequencing, his laboratory team has identified a large number of somatic mutations of the genes involved in histone modification and chromatin remodeling in tumors from the bladder, cervix, kidney, prostate, and adrenal gland. He also has a strong interest in global health and has established a pediatric cancer research effort Guatemala and Nicaragua and a cervical cancer study in Guatemala and Venezuela.

As he joins DCEG, Dr. Dean will build upon numerous past collaborations across the Division on genes involved in HIV response and Gorlin syndrome, cancers of the prostate, lung, colon, breast, colorectum, brain, and skin, as well as studies of mosaicism and the application of whole exome sequencing technology. 

“I’m delighted to pass the baton to Mike. His superb scientific accomplishments, together with his enthusiastic vision for cancer genomics will be vital assets to the Division,” said Stephen J. Chanock, M.D., Director of DCEG.