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Discovering the causes of cancer and the means of prevention

Scientific Workshop on Use of Immune Marker Panels to Uncover the Role of Inflammation in Cancer

Chronic inflammation is thought to increase the risk of several cancers, and studies show that inflammation and altered immunity play a critical role in stages of the carcinogenic process. Emerging technologies have allowed scientists to measure many immune-related markers simultaneously in a high-throughput, multiplex format.

Allan Hildesheim

In June 2014, DCEG and the Epidemiology and Genomics Research Program (EGRP) in NCI's Division of Cancer Control and Population Sciences held a workshop titled “Using Immune Marker Panels to Uncover the Role of Inflammation in Cancer.” Participants discussed their work using new multiplex inflammation marker technologies and reported findings from association studies. Workshop topics included disease associations, biological interpretation of findings, assay performance, and statistical considerations.

At the end of the workshop, participants defined areas of consensus, and identified and summarized knowledge gaps. More information, including the full workshop agenda, speakers, and topics, is available on the Immune Marker Panels Workshop website. A meeting summary will published in the peer-reviewed literature and posted to the workshop website when available.

Planning committee members from DCEG included Anil Chaturvedi, Ph.D., Allan Hildesheim, Ph.D., Chief of the Infections and Immunoepidemiology Branch, and Meredith Shiels, Ph.D.

Read more about DCEG research on immune markers and cancer.