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The following are highlighted research findings and scientific papers by DCEG investigators.

  • July 23, 2018

    Projecting Premature Death Rates for the U.S. Population Through 2030

    A new analysis by DCEG investigators and collaborators at the National Institute on Drug Abuse and the Pacific Institute for Research and Evaluation, projects future premature death rates and the number of excess deaths for the U.S. population aged 25 to 64 by race or ethnicity and sex. Their findings were published online July 20, 2018, in the journal Lancet Public Health.

  • July 20, 2018

    Low-dose radiation exposure linked to leukemia in large retrospective study

    Using data from nine historical cohort studies, investigators in the Radiation Epidemiology Branch and colleagues from other institutions, led by senior investigator Mark Little, D.Phil., were able to quantify—for the first time—excess risk for leukemia and other myeloid malignancies following low-dose exposure to ionizing radiation in childhood.

  • July 02, 2018

    Coffee consumption and mortality risk: A look at the effect of genetic variation in caffeine metabolism in the UK Biobank

    Researchers at the National Cancer Institute evaluated the coffee-drinking habits of nearly half a million people, using demographic, lifestyle, and genetic data from the UK Biobank, to determine whether genetic variation in caffeine metabolism affects associations between coffee drinking and mortality risk. The investigators confirmed previous studies showing an inverse association between coffee drinking and mortality during the study period and found similar associations in participants with genetic variants conveying both faster and slower caffeine metabolism.

  • June 20, 2018

    Agricultural Exposures, Multiple Myeloma Etiology: Profile of Tenure-track Investigator Jonathan Hofmann

    Tenure-track investigator Jonathan Hofmann, Ph.D., M.P.H., has established a research program in the Occupational and Environmental Epidemiology Branch focused on the role of agricultural exposures in the etiology of multiple myeloma and other cancers, and on understanding the biological mechanisms that influence the development and progression of multiple myeloma.

  • June 15, 2018

    Circulating Levels of Vitamin D Associated with Colorectal Cancer Risk

    A new international study by scientists from the American Cancer Society, the Harvard T.H. Chan School of Public Health, the National Cancer Institute, and more than 20 other medical centers and organizations finds that higher circulating vitamin D concentrations are significantly associated with lower colorectal cancer risk.

  • June 15, 2018

    Analgesic Use and Ovarian Cancer Risk: An Analysis in the Ovarian Cancer Cohort Consortium

    In a new study, DCEG researchers and collaborators analyzed data from 13 studies in the Ovarian Cancer Cohort Consortium (OC3) in order to prospectively investigate associations of analgesic use with ovarian cancer risk. They found that women under the age of 70 who use aspirin (or non-aspirin NSAIDS) daily or almost daily for at least six months have a ~10 percent lower risk of developing ovarian cancer than women who use it infrequently or not at all.