Skip to Content
Discovering the causes of cancer and the means of prevention

Nested Case-Control Study of Hepatocellular Carcinoma within a Health Maintenance Organization

Because the incidence of liver cancer has been increasing in the U.S., investigators in DCEG are conducting an etiologic study within a cohort of health maintenance organization (HMO) members. The cohort was enrolled in a multiphasic health examination in the early 1960s and has been followed ever since. Questionnaire data and blood samples, contributed at baseline, as well as medical records data, are being examined. Hepatitis B and hepatitis C viral infection status of all persons are being determined using the baseline blood samples. A number of hypotheses are being examined including, among others, the effect of steroid hormones on risk, the relationship with reproductive outcomes, the treatment of type II diabetes, and the treatment of obesity.

For more information, contact Katherine McGlynn.

Metabolic Epidemiology Branch - Research Areas