Investigators in the Infections and Immunoepidemiology Branch (IIB) conduct multidisciplinary studies of carefully selected domestic and foreign populations, with the goal of clarifying the relationship of infectious agents, especially viruses, to human cancer and other conditions.
IIB’s research mission is to discover infectious causes of cancer, to elucidate the determinants of malignancy for established oncogenic infections, to uncover novel infection-cancer associations, and to clarify how alterations in immunity and inflammation relate to cancer risk.
IIB investigators collaborate with researchers from a variety of disciplines in the U.S. and abroad. In addition to epidemiologic and clinical data, many IIB field studies include an extensive biological specimen collection component that allows for careful molecular testing to better define both exposures and outcomes of interest
Learn more about specific IIB research areas.
Working closely with tenured and tenure-track investigators, IIB fellows take lead responsibility for analyzing and summarizing previously collected data. Senior staff assist them in writing manuscripts and bringing these to publication in the peer-reviewed scientific literature. Fellows become familiar with the entire IIB portfolio and are encouraged to participate in on-going and newly proposed studies within the Branch and throughout the Division. Meet the current IIB fellows and learn about research training opportunities in IIB.
Sam Mbulaiteye from IIB has recently been highlighted in the Black Bag NCI Special Report/Journal of Minority Medical Students. View his interview here.
Cell illustration credit: Kristy Whitehouse
Camargo MC, et al. Divergent trends for gastric cancer incidence by anatomical subsite in US adults. Gut 2011;60:1644-9
Chaturvedi AK, et al. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 2011;29:4294-301
Engels EA, et al. Spectrum of cancer risk among US solid organ transplant recipients. JAMA 2011;306:1891-901
Kreimer AR, et al. Proof-of-principle evaluation of the efficacy of fewer than three doses of a bivalent HPV16/18 vaccine. J Natl Cancer Inst 2011;103:1444-51
O'Brien TR, et al. Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver. Genes Immun 2011;12:428-33
Shiels MS, et al. Cancer burden in the HIV-infected population in the United States. J Natl Cancer Inst 2011;103:753-62
Yu KJ, et al. Prognostic Utility of Anti-EBV Antibody Testing for Defining NPC Risk among Individuals from High-Risk NPC Families. Clin Cancer Res 2011;17:1906-14