Alter BP, Giri N. Thinking of VACTERL-H? Rule out Fanconi Anemia according to PHENOS.
Yang HP, Murphy KR, Pfeiffer RM, et al. Lifetime Number of ovulatory cycles and risks of ovarian and endometrial cancer among postmenopausal women.
Loud JT, Bremer RC, Mai PL, et al. Research participant interest in primary, secondary, and incidental genomic findings.
Khan NE, Bauer AJ, Doros L, et al. Macrocephaly associated with the DICER1 syndrome.
Mirabello L, Yeager M, Cullen M, et al. HPV 16 sublineage associations with histology-specific cancer risk using HPV whole-genome sequences in 3200 Women.
Mai PL, Best AF, Peters JA, et al. Risks of first and subsequent cancers among TP53 mutation carriers in the National Cancer Institute Li-Fraumeni syndrome cohort.
Clinical Genetics Branch (CGB) investigators study individuals at high genetic risk of cancer in order to improve our understanding of cancer etiology and to advance clinical care. This work is carried out through two major research approaches: familial studies and clinical genetics. Read about some of our contributions to improving public health for these high-risk individuals.
CGB's research mission is to conduct multidisciplinary research to advance our understanding of the molecular pathogenesis of cancer and to translate this knowledge into effective clinical applications for cancer-prone individuals and families, and for individuals at increased risk of cancer from the general population. Learn about specific CGB research areas.
The Clinical Epidemiology Unit (CEU) within CGB conducts etiologic research with potential clinical and public health applications, and leads studies evaluating population-based early detection and cancer prevention strategies.
CGB fellows work with researchers engaged in conducting clinical research studies targeting high-risk families, in pursuing astute clinical observations of unusual cancer occurrences that might provide new clues to cancer etiology, and in applying epidemiologic methods to the study of high-risk individuals. Meet the current CGB fellows and learn about research training opportunities in CGB.
Dr. Achatz, a leading geneticist from Brazil, recently joined CGB to study inherited cancer predisposition syndromes, including Li-Fraumeni syndrome, an inherited disorder that dramatically increases affected individuals’ risk for developing cancer. Learn more about Dr. Maria Isabel Achatz.