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Discovering the causes of cancer and the means of prevention

New England Bladder Cancer Study

For many years, mortality and incidence rates for bladder cancer have been higher in New England than in the rest of the country. This population-based, case-control study of bladder cancer in New Hampshire, Vermont, and Maine sought to explain the reasons for the persistent excess of rates of bladder cancer in the northern New England area.

  • Over 2,600 subjects (both cases and controls) were interviewed.
  • Data collection began in 2002 and ended in 2005.
  • Data collection activities included: personal interviews, the collection of blood, buccal cells, urine, and toenails, and the collection of drinking water samples.

Data analyses are underway to explore the use of well water from private sources, which may contain elevated levels of arsenic, in relation to the excess bladder cancer rates in New England. Also, smoking fewer cigarettes over a long time appears to be more harmful than smoking more cigarettes over a shorter time.

Map of bladder cancer mortality rates for white males, 1970-1999

Map of bladder cancer mortality rates for white females, 1970-1999

For more information, contact Dr. Debra Silverman.

Occupational and Environmental Epidemiology Branch - Research Areas