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Smokeless Tobacco

DCEG research on the association between smokeless tobacco and cancer has made a significant impact on regulation of these products.

This work began when DCEG investigators studying the U.S. Cancer Mortality Atlas observed a striking elevation of oral cancer rates among women in the rural south. In a case-control study conducted in North Carolina, elevated risk for cancer was associated with long-term use of snuff among nonsmokers, demonstrating 50-fold increased risk for tissues in direct contact with tobacco. The report published in the New England Journal of Medicine (Winn et al., 1981) stimulated congressional hearings that resulted in regulatory actions to control the advertising and labeling of smokeless tobacco and educational campaigns to reduce its use by young people.

Smokeless Tobacco: Full list of article citations

Learn about our current research on tobacco