DCEG researchers conduct studies and participate in consortial activities on cancers of the esophagus, also known as esophageal cancer. Two types of esophageal cancer are squamous cell carcinoma and adenocarcinoma, and Barrett's esophagus is a precursor lesion of esophageal adenocarcinoma. Selected studies and consortia include:
A case-control study of Barrett's esophagus and potential biomarkers
A cohort study evaluating the environmental and genetic risk factors for esophageal squamous cell carcinoma in Iran
A case-control study evaluating environmental and genetic risk factors for esophageal squamous cell carcinoma in Golestan Province, Iran
Studies initiated in 1995 to look for major susceptibility genes for upper gastrointestinal cancers and to identify the genetic changes associated with their development
Randomized controlled trials were launched in 1985 to test the effects of multiple vitamin and mineral interventions on total mortality and total and cause-specific cancer mortality in a rural Chinese population
An international consortium with epidemiologic studies of esophageal adenocarcinoma and Barrett's esophagus. Analyses so far have included reproductive factors, cigarette smoking, alcohol consumption, non-steroidal anti-inflammatory drugs, excess risk models, anthropometry, and genome-wide analyses for susceptibility loci.
An international consortium created to discuss Barrett's esophagus and its potential emergence in countries in the Eastern world