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Cancer is a complex disease driven by numerous factors: environment, lifestyle, and genetic make-up. In some cases, genetic variation shared within families is related to risk for disease. DCEG conducts research of cancer risk among families where disease occurs at a rate that exceeds that of the ‘general population’. These family studies help us to understand not only the genetic alternations related to familial cancers, but also to cancer in individuals of average risk. Selected studies include:

Telomere Biology Disorders

Researchers investigate defects in telomere biology that cause inherited bone marrow failure and cancer predisposition syndromes. Read more in DCEG Linkage newsletter