Past Events

Diet and Cancer: Harnessing Emerging Technologies to Advance Etiologic Research and Improve Nutritional Assessment - Dr. Loftfield

DCEG Stadtman Seminar

Diet and Cancer: Harnessing Emerging Technologies to Advance Etiologic Research and Improve Nutritional Assessment

Comparing Alternatives for Estimation from Nonprobability Samples - Dr. Valliant

Biostatistics Branch Seminar Series

Three approaches to estimation from nonprobability samples are quasi-randomization, superpopulation modeling, and doubly-robust estimation. In the first, the sample is treated as if it was obtained via a probability mechanism but, unlike in probability sampling, that mechanism is unknown. Pseudo selection probabilities of being in the sample are estimated by using the sample in combination with some external data set that covers the desired population.

Measuring the Mortality Reductions Produced by Organized Cancer Screening: A Principled Approach - Dr. Hanley

Biostatistics Branch Seminar Series

In cancer screening trials and population-based comparisons, mortality reductions are usually summarized by an overall (single-number) mortality reduction. This proportional hazards model is logically untenable. I describe a model Liu et al. (IntStatRev2015) for the expected reductions in each (Age,Year) cell of a Lexis diagram.

Analysis of Extreme Conditional Quantiles - Dr. Wang

Biostatistics Branch Seminar Series

An important problem in many fields is the modeling and prediction of events that are rare but have significant consequences. Unexpectedly heavy rainfall, large portfolio loss, and dangerously low birth weight are some examples of rare events.

Molecular Epidemiology of Gynecologic Cancers: Moving Etiology Findings to Clinical Applications - Dr. Clarke

DCEG Stadtman Seminar

Moving etiologic findings to clinical applications

"The Tragedy of the (Data) Commons" - Dr. Hendler

DCEG Seminar

The tragedy of the commons, first proposed by William Lloyd in 1833, is an economic problem in which every individual has an incentive to consume a resource at the expense of every other individual with no way to exclude anyone from consuming. It results in overconsumption, under investment, and ultimately depletion of the resource.

Computational Biology of DNA-Repair in Adult and Pediatric Cancers - Dr. Glodzik

We extended the computational methods for analysis of mutation signatures in order to describe patterns of chromosomal rearrangements. In particular, the rearrangement signatures enable the assessment of proficiency of homologous recombination (HR). HRDetect, an algorithm we developed, predicts probability of HR-deficiency, and is based on holistic portrayal of mutational signatures across different classes of somatic mutations.

Collaborating Across Disciplines for Cancer Discovery and Translation - Dr. Platz

DCEG Visiting Scholar Seminar

Modern Genetic Analysis on The Cloud - Dr. Hartley

Biostatistics Branch Seminar Series

Harnessing Rare Somatic Variants for Tumor Classification - Shen

Biostatistics Branch Seminar Series

In recent years there has been extensive investigation of the mutational landscape of the cancer genome from large-scale sequencing studies. However, the bulk of the attention has focused on major cancer genes, and especially the hot spot mutations in these genes at which mutations occur frequently.