Kelvin C. de Andrade, Ph.D., M.Sc.
Kelvin César de Andrade joined the Clinical Genetics Branch (CGB) as a predoctoral fellow in 2015, under the NIH Graduate Partnership program. He earned both his master's degree and doctorate in Oncology from the A.C. Camargo Cancer Center, São Paulo, Brazil. After successfully defending his dissertation “Prevalence of potentially pathogenic germline TP53 variants in population databases” in 2018, he transitioned to postdoctoral fellow. He was promoted to research fellow in 2021 and to staff scientist in 2026.
As a staff scientist working with Sharon Savage, M.D., Director and senior investigator, Dr. de Andrade studies the genetic and epidemiologic factors underlying cancer risk, disease progression, and phenotypic variability in individuals with hereditary cancer predisposition syndromes, with a particular focus on Li-Fraumeni syndrome and telomere biology disorders. His research integrates genomic, epidemiologic, and real-world data approaches to identify modifiers of disease risk and severity, characterize the clinical manifestations of rare genetic disorders, and improve disease prevention, risk assessment, and patient management. Dr. de Andrade also serves as coordinator of the NCI-sponsored TP53 Database, an international resource that collects clinical, genetic, and functional data on TP53 variants and Li-Fraumeni syndrome.