Megan Frone, M.S., C.G.C.

Biography

Megan Frone, M.S., L.G.C., is a Genetic Counselor in the Clinical Genetics Branch (CGB). She provides genetic education and counseling to participants across the CGB clinical studies and is the lead genetic counselor for the Li-Fraumeni Syndrome (LFS) Study and the RASopathies Study. Her responsibilities also include variant annotation and curation for clinical and research activities within DCEG and for ClinGen. She is the coordinator of the ClinGen TP53 Variant Curation Expert Panel.

Ms. Frone came to CGB from the University of Texas Southwestern Medical Center, Dallas, where she worked as an adult and pediatric cancer genetics counselor and Genetic Counseling Supervisor. She previously worked in the inborn errors of metabolism, Down syndrome, and general pediatrics genetics clinics at Children’s Health, also in Dallas.

Ms. Frone holds a B.S. in biology, with a concentration in cell and molecular biology, from SUNY Binghamton University, New York, and an M.S. in genetic counseling from Virginia Commonwealth University in Richmond with a Virginia Leadership Education in Neurodevelopmental Disabilities (Va-LEND) Diplomate.

Research Interests

• Genetic susceptibility to cancer
• Risk communication
• Variant bioinformatics, annotation, and curation
• Interpretation and reporting of genomic results