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Discovering the causes of cancer and the means of prevention

Laboratory of Translational Genomics Opportunities with Specific Investigators

Genetics and Genomics of Pancreatic Cancer - Postdoctoral Fellowship

Dr. Laufey Amundadottir, senior investigator in the Laboratory of Translational Genomics, is seeking a highly motivated individual interested in using genetic and genomic approaches to understand the functional consequences of carrying inherited pancreatic cancer risk variants. The lab is highly interdisciplinary and uses state-of-the-art 'omics technologies, including various high-throughput, sequence-based approaches to assess gene expression, splicing, chromatin interactions, and gene regulatory effects. In parallel, a wide variety of molecular and cell biology methods are applied to evaluate the biological consequences of altered regulation or function of susceptibility genes on phenotypes associated with cancer predisposition. The successful candidate will investigate cell type specific effects of inherited risk alleles using sorted populations of pancreatic acinar, ductal and islet cells, as well as the effects of inflammation on molecular phenotypes related to pancreatic cancer risk.

The successful candidate will be mentored to learn new methods and approaches in genetics, genomics, and functional biology, present their work at national and international meetings, publish high impact papers, network with others in the field, and prepare for an independent research career.

Qualifications: Candidates must have a Ph.D. in molecular biology, genetics, cell biology or biochemistry, and no more than five years of postdoctoral experience. We seek curious and self-motivated individuals with a strong background in genomic and molecular biology methods and an interest in using cutting edge 'omics approaches. Experience with computational analysis of large-scale genetic and genomic datasets is a plus, as well as a strong publication record and effective written and verbal communication skills.

For more information about this position, contact Dr. Amundadottir.

To Apply: Submit a cover letter, CV, and names of three references to Dr. Laufey Amundadottir.

Review of applications will continue until the position is filled. Applicants may be U.S. citizens, permanent residents; or foreign nationals (visa requirements apply). Candidates are subject to a background investigation. DHHS, NIH, and NCI are Equal Opportunity Employers and dedicated to building a diverse community in their training and employment programs.