Preconception, prenatal and early childhood radiation exposure and risk of pediatric cancer - Martha Linet, M.D.
DCEG Events
September 14, 2016 | 12:30 PM – 2:30 PM
NCI Bethesda Bethesda, MD
Martha Linet
NIH Research Festival Symposium Presentation
Martha Linet, M.D., M.P.H. will present "Preconception, prenatal and early childhood radiation exposure and risk of pediatric cancer" as part of an NIH Research Festival symposium titled "Lasting legacies: Long-term effects of early developmental exposure."
It is increasingly apparent that environmental exposures, particularly during developmentally sensitive time windows, can impact on later health outcomes in children and adults. Although this was a novel idea that encountered widespread skepticism when first proposed more than 25 years ago, it is now generally accepted due to robust documentation of these effects in both animal models and humans. Now known as DOHaD (Developmental Origins of Health and Disease), the field is moving toward defining the mechanisms by which early exposures modulate long-term physiology. This symposium will group intramural investigators from several ICs to highlight new evidence for DOHaD in human health outcomes as well as current data regarding the underlying mechanisms.