Integrative Tumor Epidemiology Branch
Integrating molecular pathology, somatic and germline genomics, and epidemiology to identify environmental and germline risk for cancer
ITEB Highlights
Characterization of breakpoint regions of large structural autosomal mosaic events. Hum Mol Genet 2017; Machiela MJ, Jessop L, Zhou W, et al.
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nat Genet 2017; Milne RL, Kuchenbaecker KB, Michailidou K, et al.
Genetic variants related to longer telomere length are associated with increased risk of renal cell carcinoma. Eur Urol 2017; Machiela MJ, Hofmann JN, Carreras-Torres R, et al.
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet 2017; McKay JD, Hung RJ, Han Y, et al.
Age-related terminal duct lobular unit involution in benign tissues from Chinese breast cancer patients with luminal and triple-negative tumors. Breast Cancer Res 2017; Guo C, Sung H, Zheng S, et al.
Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet 2017; Wang Y, McKay JD, Rafnar T, et al.
Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast. Int J Cancer 2017; Bodelon C, Oh H, Chatterjee N, et al.
Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients. Breast Cancer Res 2017; Mullooly M, Yang HP, Falk RT, et al.
The Integrative Tumor Epidemiology Branch (ITEB) employs molecular pathology, somatic and germline genomics, and epidemiology to identify environmental and germline risk factors for cancer.
Research Mission
The mission of ITEB is to advance understanding of cancer etiology and progression through integrative analyses of environmental and germline risk factors with comprehensive data on histological and molecular profiling of tumors and their precursors, including somatic genomic analyses. The branch also develops methods to support this cutting-edge research.
Fellowships
ITEB provides a dynamic and collaborative environment for trainees at the pre- and post-doctoral level. Meet the current ITEB fellows and learn about research training opportunities in ITEB.