Integrative Tumor Epidemiology Branch
Integrating molecular pathology, somatic and germline genomics, and epidemiology to identify environmental and germline risk for cancer
The Integrative Tumor Epidemiology Branch (ITEB) employs molecular pathology, somatic and germline genomics, and epidemiology to identify environmental and germline risk factors for cancer.
Research Mission
The mission of ITEB is to advance understanding of cancer etiology and progression through integrative analyses of environmental and germline risk factors with comprehensive data on histological and molecular profiling of tumors and their precursors, including somatic genomic analyses. The branch also develops methods to support this cutting-edge research.
Fellowships
ITEB provides a dynamic and collaborative environment for trainees at the pre- and post-doctoral level. Meet the current ITEB fellows and learn about research training opportunities in ITEB.
ITEB Highlights
Using deep convolutional neural networks to identify and classify tumor-associated stroma in diagnostic breast biopsies. Mod Pathol 2018; Ehteshami Bejnordi B, Mullooly M, Pfeiffer RM, et al.
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility. Nat Commun 2018; Machiela MJ, Grünewald TGP, Surdez D, et al.
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation. Int J Cancer 2018; Abubakar M, Chang-Claude J, Ali HR, et al.
Mosaic Y loss is moderately associated with solid tumor risk. Cancer Res 2019, Epub 2018; Loftfield E, Zhou W, Yeager M, et al.
Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Hum Mol Genet 2018; Gu F, Chen TH, Pfeiffer RM, et al.
Black-White breast cancer incidence trends: Effects of ethnicity. J Natl Cancer Inst 2018; Davis Lynn BC, Rosenberg PS, Anderson WF, et al.