Lindsay Morton, Ph.D.
|Organization:||National Cancer InstituteDivision of Cancer Epidemiology & Genetics, Radiation Epidemiology Branch|
|Address:||NCI Shady GroveRoom 7E454|
Dr. Morton received a B.A. from Dartmouth College and a Ph.D. in epidemiology from Yale University with a focus on cancer epidemiology. She joined DCEG in 2004 as a postdoctoral fellow with a concentration in molecular epidemiology. During her doctoral and postdoctoral training, she focused her research on understanding the causes of lymphoid neoplasms.
In 2008, Dr. Morton joined the Radiation Epidemiology Branch (REB) as a tenure-track investigator. She expanded her research to the study of multiple primary cancers, evaluating the carcinogenic effects of radiotherapy and chemotherapy, as well as other environmental and genetic risk factors for second cancers. In 2015, Dr. Morton was awarded scientific tenure by NIH and became a senior investigator.
Dr. Morton has been recognized for her research contributions with an NCI Career Development Innovation Award, an NIH Merit Award, and an NCI Director’s Award. In addition, she received the DCEG Mentoring Award in recognition of her strong commitment to training junior scientists.
In recent decades, new treatments and early detection have dramatically improved survival following a cancer diagnosis. However, new malignancies, or “second cancers,” are a leading cause of morbidity and mortality among survivors. The overarching goal of Dr. Morton’s research program is to quantify the risk of second cancers in different groups of cancer survivors, and to elucidate the causes of second cancers. The results from her studies can be used to better understand the biology of cancer and to inform clinical practice (e.g., treatment risks and benefits and long-term follow-up of cancer survivors).
With rapid advances in technology in the last decade, scientists have dramatically increased their understanding of cancer predisposition, finding inherited genetic markers that are associated with risk for a particular disease. Dr. Morton is leading DCEG efforts to identify genetic variants associated with the development of second cancers, either independent of treatment exposures or that act jointly with specific treatments. Key studies in this collaboration are the Childhood Cancer Survivor Study and NCI’s Long-Term Follow-Up Study of Retinoblastoma Survivors, both of which have the rare combination of detailed medical record data, long-term follow-up of childhood cancer survivors with information on occurrence of second cancers, and available DNA.