Research Highlights - News Updates
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Special issue of Preventive Medicine argues the case for HPV testing to prevent cervical cancer
In February 2017, DCEG experts and colleagues from around the world presented the evidence in favor of phasing out cytology-based screening in favor of the more sensitive HPV testing.
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Using Geographic Information Systems to Improve Exposure Assessment in Epidemiological Studies of Cancer
Description of epidemiologic studies that are using geographic information system (GIS) technology, recently-available data resources, and novel analytic methods to home in on environmental causes of cancer.
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Study Finds Premature Death Rates Diverge in the United States by Race and Ethnicity
Premature death rates have declined among Hispanic, Black, and Asian/Pacific Islander—but increased among White and American Indian/Alaska Native adults, according to a comprehensive study of premature death rates for the entire U.S. population from 1999 to 2014.
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TCGA study identifies genomic features of cervical cancer
Novel genomic and molecular characteristics of cervical cancer will aid in subclassification of the disease and may help target therapies that are most appropriate for each patient.
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Top Scientific Publications from 2016
Summary of our top papers from 2016
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New Model More Accurately Predicts Breast Cancer Risk in Hispanic Women
A new breast cancer risk prediction model, published in the Journal of the National Cancer Institute, will help health care providers more accurately predict breast cancer risk in their Hispanic patients.
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Patient at NIH Clinical Center Provides Invaluable Resource for the Study of Cancer’s Evolution
In a departure from the typical “big data” approach, scientists from around the world have collaborated to learn from an individual case, carefully documented by an international group of scientists over nearly 30 years.
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Low-intensity smokers are at increased risk of earlier death
People who consistently smoked less than one cigarette per day over their lifetime had a 64 percent higher risk of earlier death than never smokers
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Celebrating 15 Years of the Cancer Genomics Research Laboratory
October 2016 marks the 15th anniversary of the founding of the DCEG Cancer Genomics Research (CGR) Laboratory. From the outset, CGR has responded to new scientific opportunities by incorporating the latest technologies, enabling DCEG investigators to be at the cutting edge of discovery.
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Genetic and environmental factors influence APOBEC mutagenesis in tumors
Genetic and environmental factors influence APOBEC mutagenesis in tumors
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BMI Outside Normal Range Associated with Increased Risk of Mortality
A study co-led by DCEG researchers confirms body mass index (BMI) outside of the normal range (20-24.9) is associated with increased risk of mortality, confirming results from a 2010 NEJM report.
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Computer-based coding increases efficiency of risk assessments in studies of occupational exposures
SOCcer (Standardized Occupation Coding for Computer-assisted Epidemiologic Research) is an algorithm to efficiently identify, classify, and code occupations.
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Enhanced Risk-Based Lung Cancer Screening May Prevent More Deaths than Current Approaches
Cancer Currents Blog Post: NCI researchers have developed a risk model-based approach for selecting smokers and former smokers who may be candidates for lung cancer screening with low-dose computed tomography (CT).
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Charting a Course toward Precision Cancer Prevention
Dr. Stephen Chanock discusses risk prediction for breast cancer in women of European background in the United States in the Cancer Currents Blog.
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First-ever serial collection of dysplastic nevi and melanomas launched
DCEG produces online catalogue with serial images of dysplastic nevi, normal moles, and melanoma.
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Increased physical activity associated with lower risk of 13 types of cancer
New study of physical activity and cancer shows greater levels of leisure-time physical activity associated with a lower risk.
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Arsenic in Drinking Water from Private Wells Linked to Elevated Bladder Cancer Risk in New England
Private wells, particularly dug wells established during the first half of the 20th century, may have contributed to the elevated risk of bladder cancer that has been observed in Maine, New Hampshire, and Vermont for over 50 years.
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DCEG Study Design Tools: Power for Genetic Association Analyses (PGA)
On June 6, 2018, DCEG hosted a half-day session with several editors and contributors to the fourth edition of Cancer Epidemiology and Prevention, published by Oxford University Press in November 2017.
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Shedding Light on the Etiology of Male Breast Cancer
Drs. Louise Britton and Michael Cook investigate the etiology of male breast cancer
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Clinical Genetics Branch Discovery: RTEL1 Founder Mutation Among Ashkenazi Jews
Clinical Genetics Branch Discovery: RTEL1 Founder Mutation Among Ashkenazi Jews - reported in the Spring 2016 issue of Linkage newsletter, published by the NCI Division of Cancer epidemiology & Genetics