2023 - News Updates
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Douglas Stewart Elected a Member of the American Society for Clinical Investigation
In December 2023, Dr. Stewart, senior investigator in the Clinical Genetics Branch, was elected a member of the American Society for Clinical Investigation, one of the nation’s oldest medical honor societies.
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Blanche Alter Receives Lifetime Achievement Award at 2023 ASH Annual Meeting
In December 2023, at the American Society of Hematology Annual Meeting, Dr. Blanche Alter received the Wallace H. Coulter Award for Lifetime Achievement in Hematology, in recognition of her numerous accomplishments in bone marrow failure research.
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Chromosomal Mosaicism May Influence Risk for Burkitt Lymphoma in Children from sub-Saharan Africa
A multi-disciplinary, international team of experts identified differences in the number of mosaic chromosomal alterations (mCAs) in children from sub-Saharan Africa with Burkitt lymphoma (BL), compared to children without BL. Similar patterns were observed in sub-Saharan African adults. These findings suggest a role for environmental factors in the frequency of mCAs in sub-Saharan African individuals and indicate mCAs in circulating leukocytes could have relevance for future BL risk. These novel findings were published in Nature Communication on December 6, 2023.
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Intramural Research on Hispanic/Latino Populations Meeting
The NIH Intramural Research on Hispanic/Latino Populations Meeting was held in December to promote trans-NIH research collaborations to address health disparities among Hispanic/Latino populations, who are underrepresented in health research. Drs. Constanza Camargo and Katherine McGlynn were two of the meeting organizers.
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2024 Sallie Rosen Kaplan Fellowship Recipient
Dr. Minal B. Patel in the Laboratory of Translational Genomics was selected for the 2024 Sallie Rosen Kaplan Fellowship program.
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AACR Video Features Stephen Chanock: A Career Committed to Defeating Cancer
Stephen Chanock was featured as part of the American Association for Cancer Research (AACR) Stories series in a video titled, "A Career Committed to Defeating Cancer."
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Childhood Leukemia Linked to PFAS Levels Measured in Mother's First Trimester
Rena Jones, Mary Ward, and colleagues, observed increasing concentrations of a specific per- and polyfluoroalkyl substances (PFAS) in the serum of pregnant women to be associated with increased risk of acute lymphoblastic leukemia in their offspring. Investigators in the Occupational and Environmental Epidemiology Branch are the first to explore the association between prenatal PFAS exposure and risk of childhood leukemia. Their findings were published in the Journal of the National Cancer Institute.
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Both Smoking-attributable and Smoking-unrelated Lung Cancer Death Rates Continue to Decline
Smoking-attributable and smoking-unrelated lung cancer death rates declined from 1991 to 2018 in the U.S., according to a new study from Dr. Meredith Shiels and colleagues.
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Anal Cancer Risk and Survival in People with HIV
A series of studies using data from the HIV/AIDS Cancer Match Study provide evidence to inform recommendations for anal cancer screening and emphasize the importance of early anal cancer detection and treatment among people with HIV. The papers were published by Drs. Haas and Shing, part of Dr. Shiels’s research group. The findings
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NIH Intramural Research Program Features Senior Investigator Shahinaz Gadalla
Shahinaz Gadalla, M.D., Ph.D., discusses her research on stem cell transplants and the path to improving survival for the NIH Intramural Research Program's news column, "Research in Action."
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Bryan Valcarcel Selected for 2023 ASH Clinical Research Training Institute Program
Bryan Valcarcel, M.D., M.P.H., postdoctoral fellow in REB, was selected for the ASH's Clinical Research Training Institute (CRTI) program, whose goal is to produce innovative leaders in clinical hematology.
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NIH Intramural Blog Profiles Postdoctoral Fellow Richard Remigio
Dr. Richard Remigio, a postdoctoral fellow in the Occupational and Environmental Epidemiology Branch, discusses his work on the health repercussions of changing environmental conditions in NIH’s Intramural Research Program (IRP) blog, I am Intramural.
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Mary Lou McMaster, Senior Clinician Specialist, Retires from DCEG
Mary L. McMaster, M.D., senior clinical specialist in the clinical genetics Branch, and captain in the U.S. Public Health Service, retired from DCEG in December 2023. Dr. McMaster devoted nearly 25 years to longitudinal studies of families with rare cancer predisposition syndromes.
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2024 DCEG Fellows Awards for Research Excellence
DFAREs recognize the outstanding scientific research performed by DCEG fellows and provides funding for travel to scientific meetings or conferences.
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Poor Sleep Quality Associated with Increased Prostate Cancer Risk
Poor sleep quality, as measured by accelerometers, was associated with a 15-20% greater risk of prostate cancer in a study of over 30,000 men in the UK Biobank. Neither sleep duration nor sleep timing were associated with prostate cancer risk. These novel findings need to be replicated in future studies and in more diverse study populations.
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Differences in Knowledge of HPV and the HPV Vaccine by Education, Race, and Ethnicity
Ms. Erica Stephens and Dr. Jaimie Shing used data from a nationally representative sample of U.S. adults to ascertain awareness of HPV and the HPV vaccine, as well as knowledge that HPV can cause cancers, by educational attainment, race, and ethnicity. They found profound disparities that signal the importance of continued education around HPV and the HPV vaccine.
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Clinical Director’s Corner: New Infrastructure for Family Studies’ Data
Sharon Savage, M.D., DCEG Clinical Director, describes the new, modern infrastructure for Family Studies conducted by the Clinical Genetics Branch. CHARMS is an interactive patient- and provider-facing platform for the recruitment and management of participants in CGB studies. "Clinical Director's Corner" is a new, recurring feature of Linkage, DCEG's newsletter. It will alternate with updates from Pete Kraft, Ph.D., Director of the Trans-Divisional Research Program, and Jackie Lavigne, Ph.D., M.P.H., Director of the Office of Education.
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PFAS and Cancer: Occupational and Environmental Epidemiology Branch Research on “Forever Chemicals”
Researchers in the Occupational and Environmental Epidemiology Branch (OEEB) investigate potential cancer risks associated with exposure to PFAS, also known as “forever chemicals.” Learn about the findings from recent publications.
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2023 NCI Scientific Investigators Retreat
Constanza Camargo and Steve Moore presented their research; Mia Gaudet received the Women Scientist Advisors (WSA) Mentoring Award and investigators presented posters, engaged in small-group discussions, and learned about the research of their colleagues in the Center for Cancer Research.
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2023 iCURE Scholars Welcomed to DCEG
Atuahene Adu-Gyamfi, Quiera Booker, Macy Corley, Michael Kebede, Mona Miraftab, Paloma Mitra, and Erica Stephens are the 2023 incoming NCI Intramural Continuing Umbrella of Research Experiences (iCURE) Program Scholars.