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R Package for Non-parametric estimation of the age-at-onset distribution from a cross-sectional sample

Description

This code implements an expectation-maximization (EM) algorithm to non-parametrically estimate the age-of-onset distribution for a disease from a cross-sectional sample of the population that includes individuals with prevalent disease. The method accommodates categorical covariates and can be used to obtain unbiased estimates of the covariate distribution in the source population.

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Reference

Non-parametric estimation of  the age-at-onset distribution from a cross-sectional sample. Soutrik Mandal, Jing Qin,  Ruth M. Pfeiffer, Biometrics

Support

Questions, please contact Dr. Ruth Pfeiffer (pfeiffer@nih.gov)

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