Skip to main content
An official website of the United States government
Email

R Package for Non-parametric estimation of the age-at-onset distribution from a cross-sectional sample

Description

This code implements an expectation-maximization (EM) algorithm to non-parametrically estimate the age-of-onset distribution for a disease from a cross-sectional sample of the population that includes individuals with prevalent disease. The method accommodates categorical covariates and can be used to obtain unbiased estimates of the covariate distribution in the source population.

Download R Package

Reference

Non-parametric estimation of  the age-at-onset distribution from a cross-sectional sample. Soutrik Mandal, Jing Qin,  Ruth M. Pfeiffer, Biometrics

Support

Questions, please contact Dr. Ruth Pfeiffer (pfeiffer@nih.gov)

  • Updated:

If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. In the case of permitted digital reproduction, please credit the National Cancer Institute as the source and link to the original NCI product using the original product's title; e.g., “R Package for Non-parametric estimation of the age-at-onset distribution from a cross-sectional sample was originally published by the National Cancer Institute.”

Email