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Risk Assessment Macros, Software Programs, and Tools

The following risk assessment tools were developed by DCEG investigators. They are freely available for use by other researchers.

Breast Cancer

BCRA R Package

BCRA is an R package that projects absolute risk of invasive breast cancer according to NCI’s Breast Cancer Risk Assessment Tool (BCRAT) algorithm for specified race/ethnic groups and age intervals.

Breast Cancer Risk Assessment SAS Macro (Version 4, Gail Model)

A SAS macro (commonly referred to as the Gail Model) that projects absolute risk of invasive breast cancer according to NCI’s Breast Cancer Risk Assessment Tool (BCRAT) Online Calculator algorithm for specified race/ethnic groups and age intervals. 

Asian Pacific Islander American Women - Breast Cancer Risk Assessment SAS Macro

Software that projects absolute breast cancer risk over defined age intervals for Asian and Pacific Islander American women with specific risk factors.

CARE Model SAS Macro: Breast Cancer Risk Assessment for African American Women

The CARE Model is a SAS macro that allows researchers to estimate an African American woman's risk of developing invasive breast cancer over specified age intervals.

Breast Cancer with Mammographic Density Risk Assessment SAS Macro

A SAS macro that projects absolute invasive breast cancer risk for white women based on measurements of mammographic density and other risk factors.

Breast, Endometrial, and Ovarian Risk Assessment SAS Macros

Software that projects absolute risk for breast, endometrial, and ovarian cancer in Caucasian and African American women.

(Hisp)anic-American (BrCa) (R)isk (A)ssessment (M)acro

Breast Cancer Risk Prediction macro for projecting risk for Hispanic Americans.

Colon Cancer

Colon Cancer Risk Assessment - SAS Macro

A SAS macro developed by experts in the Biostatistics Branch that projects absolute risk of colon cancer according to NCI’s Colorectal Cancer Risk Assessment Tool (CCRAT): Online Calculator algorithm.

Colon Cancer Risk Assessment - Gauss Program

An executable file (in GAUSS) developed by experts in the Biostatistics Branch that projects absolute colon cancer risk (with confidence intervals) according to the Colorectal Cancer Risk Assessment Tool (CCRAT): Online Calculator algorithm. GAUSS is not needed to run the program.

Calculator of Colorectal Cancer Cure Probability

Calculator of Colorectal Cancer Cure Probability was developed for use by health professionals to estimate the probability that a patient with colorectal cancer is cured of their cancer. This probability may be useful for counseling patients and clinical decision-making.

Lung Cancer

Lung Cancer Risk Assessment Tool

Statistical analysis tool that predicts a person's risk of lung cancer diagnosis and death based on a series of demographic and clinical risk factors for lung cancer.

Lung Cancer Risk Models for Screening (R package: lcrisks)

A model developed by experts in the Biostatistics Branch to calculate individual risks of lung cancer and lung cancer death based on covariates: age, education, sex, race, smoking intensity/duration/quit-years, body mass index, family history of lung cancer, and self-reported emphysema. This package also estimates the Life Years Gained From Screening-CT.

lcmodels

An R package developed by experts in the Biostatistics Branch that provides individual risks of lung cancer and lung cancer death based on published data. This package also estimates the Life Years Gained From Screening-CT. 

Risk-based NLST Outcomes Tool (RNOT)

This tool developed by experts in the Biostatistics Branch uses basic information on smoking behavior and data from the National Lung Cancer Screening Trial (NLST) to determine the following utility of lung cancer screening, five-year risk of lung cancer diagnosis or mortality, and risk of a false-positive test result.

Melanoma

Melanoma Risk Assessment Tool 

Download code for the NCI Melanoma Risk Assessment Tool (MRAT): Online Calculator, developed by DCEG investigators for use by health professionals to estimate a patient's absolute risk of developing invasive melanoma. 

Moles to Melanoma: Recognizing the ABCDE Features

The Moles to Melanoma Tool: Recognizing the ABCDE Features provides information about and examples of common moles, dysplastic nevi (atypical moles) and melanoma. This collection does not include any pictures of non-melanoma types of skin cancer (e.g. basal cell or squamous cell). Since they arise from different cell types in the skin, they look very different from melanoma. 

Thyroid Cancer

Thyroid Cancer Risk Assessment Tool (TCRAT)

An R package risk prediction model developed by experts in the Biostatistics Branch to calculate the absolute risk of developing a second primary thyroid cancer in individuals who were diagnosed with cancer during their childhood.

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