Research Highlights - News Updates

Summaries of research conducted by DCEG investigators.

APOBEC3-Induced Mutations in HPV 16 Viral Clearance
- By DCEG Staff
- February 28, 2020
Bin Zhu, in the Biostatistics Branch, and Lisa Mirabello, in the Clinical Genetics Branch, conducted the largest HPV 16 whole-genome sequencing study to evaluate the contribution of genetic variation in HPV 16 to infection outcome. They found APOBEC3-induced mutations associated with benign cervical infections.
Decline in U.S. Hepatocellular Carcinoma Rates
- By DCEG Staff
- January 21, 2020
Overall U.S. hepatocellular carcinoma (HCC) incidence rates plateaued in 2013 and dropped 4% in 2016 according to findings published in Gastroenterology on January 19, 2020.
Metformin Use for Type 2 Diabetes May Reduce Cancer Risk in Myotonic Dystrophy Type 1
- By DCEG Staff
- January 14, 2020
Type 2 diabetes in patients with myotonic dystrophy type 1 was associated with excess risk of cancer, but metformin treatment may reduce this risk, according to findings in the International Journal of Cancer on November 20, 2019.