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Research Highlights - News Updates

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Summaries of research conducted by DCEG investigators.

  • Progress Assessing Cancer Risk Using Clinical Practice Research Datalink
    • By Maura Kate Costello, M.A.

    DCEG scientists use data from the Clinical Practice Research Datalink to investigate risk factors and exposures that may contribute to cancer risk, ranging from medication usage to genetic cancer predisposition.

  • APOBEC3-Induced Mutations in HPV 16 Viral Clearance
    • By DCEG Staff

    Bin Zhu, in the Biostatistics Branch, and Lisa Mirabello, in the Clinical Genetics Branch, conducted the largest HPV 16 whole-genome sequencing study to evaluate the contribution of genetic variation in HPV 16 to infection outcome. They found APOBEC3-induced mutations associated with benign cervical infections.

  • Decline in U.S. Hepatocellular Carcinoma Rates
    • By DCEG Staff

    Overall U.S. hepatocellular carcinoma (HCC) incidence rates plateaued in 2013 and dropped 4% in 2016 according to findings published in Gastroenterology on January 19, 2020.

  • Metformin Use for Type 2 Diabetes May Reduce Cancer Risk in Myotonic Dystrophy Type 1
    • By DCEG Staff

    Type 2 diabetes in patients with myotonic dystrophy type 1 was associated with excess risk of cancer, but metformin treatment may reduce this risk, according to findings in the International Journal of Cancer on November 20, 2019.

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