Linkage Newsletter - DCEG News Updates
Longer-format articles that go in-depth on DCEG research or profile investigators. These articles are distributed three times each year as the DCEG Newsletter, Linkage.
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NIH-AARP Diet and Health Study Reaches Milestone
Nearly 25 years ago, NCI investigators mailed over three million members of the AARP a food frequency questionnaire to examine the relationship between diet, lifestyle, and cancer risk among older Americans. With the response of over half a million people, the NCI launched the NIH-AARP Diet and Health Study, a cohort that was, and remains, the largest prospective in-depth study on diet and health.
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Molecular and Digital Pathology Laboratory Expands Capacity for DCEG Studies
The Molecular and Digital Pathology Laboratory is an extension of the Cancer Genomics Research Laboratory that integrates histological and molecular tissue profiling with analyses of environmental and genetic risk factors in epidemiologic studies.
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Bone and Soft Tissue Sarcoma Risk Patterns Among Survivors of Hereditary Retinoblastoma
Long-term risk of bone and soft tissue sarcomas after treatment for hereditary retinoblastoma varies by age, location and sex, according to a study published in the Journal of Clinical Oncology on October 17, 2019.
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Cook Awarded Scientific Tenure by the NIH
Dr. Michael B. Cook was awarded scientific tenure by the NIH and promoted to senior investigator in the Metabolic Epidemiology Branch.
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Aspirin Use Associated with Increased Survival in Biliary Tract Cancer
Aspirin use after biliary tract cancer (BTC) diagnosis was associated with increased patient survival, according to a study by DCEG investigators published in JAMA Oncology on October 17, 2019.
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New Reports Highlight the Critical Role of Physical Activity for Cancer Prevention, Treatment, and Survival
Roundtable on Exercise and Cancer updates the evidence on physical activity for the prevention of multiple cancer types, and the importance of exercise for cancer patients and survivors to improve their physical and psychological health.
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HPV Vaccine May Provide Men with Herd Immunity against Oral HPV Infections
Oral HPV infections among unvaccinated men dropped 37% in 2009-2016 which may be a result of herd immunity by the HPV vaccine.
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Weinberg Delivers 2019 Wacholder Lecture
Clarice Weinberg delivered the 2019 Sholom Wacholder Distinguished Lecture on Evidence for Familial Clustering of Breast Cancer Age at Onset.
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Sir John Burn Delivers Seminar on Prediction and Prevention of Colorectal Cancer in Patients with Lynch Syndrome
In July 2019, Sir John Burn spent two days with DCEG staff and fellows as a Visiting Scholar during which time he delivered an informative seminar on prediction and prevention of colorectal cancer in patients with Lynch Syndrome.
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Trabert Granted DoD Investigator-Initiated Research Award
Britton Trabert received a Department of Defense Investigator-Initiated Research Award for her proposal titled “Making the CASE: Chemopreventive use of ASpirin for ovarian cancer—integrating Epidemiological data to evaluate population subgroups and tumor expression.”
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Risk for Treatment-related Leukemia after Chemotherapy for Childhood Cancer has Increased Over Last 45 years
Risk of therapy-related myelodysplastic syndrome and acute myeloid leukemia (tMDS/AML) after initial chemotherapy for childhood cancer has significantly increased between 1975 and 2015, according to a new analysis by Pragati Advani, Ph.D., and colleagues.
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The Unique Role of Staff Clinicians in DCEG Research
Staff clinicians operate at the intersection of clinical care and research on natural history studies of families with cancer predisposition syndromes like Inherited Bone Marrow Failure (IBMFS) and Li-Fraumeni Syndrome (LFS).
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Controlling Cervical Cancer: DCEG’s Ongoing Commitment to Improving Women’s Health
Scientists in DCEG are among the leaders of a growing global effort to greatly reduce deaths from cervical cancer
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Laboratory of Translational Genomics Celebrates 10th Anniversary with Symposium
In December 2018, DCEG hosted a day-long symposium in celebration of the 10th anniversary of the founding of the Laboratory of Translational Genomics (LTG). The symposium highlighted the history and key discoveries of the LTG and its investigators.
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Understanding the Etiology of Gynecologic Cancers: Profile of Tenure-Track Investigator Britton Trabert
Tenure-track investigator Britton Trabert, Ph.D., M.S., studies the epidemiology of ovarian cancer and the hormonal etiology of gynecologic cancers.
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Metabolomics: The Growing Potential of an Emerging Field
DCEG scientists have been evaluating the performance of metabolomics assays and applying them to studies of cancer etiology.
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Agricultural Exposures, Multiple Myeloma Etiology: Profile of Tenure-track Investigator Jonathan Hofmann
Tenure-track investigator Jonathan Hofmann, Ph.D., M.P.H., has established a research program in the Occupational and Environmental Epidemiology Branch focused on the role of agricultural exposures in the etiology of multiple myeloma and other cancers, and on understanding the biological mechanisms that influence the development and progression of multiple myeloma.
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Death Before Old Age: Untangling Premature Mortality in the U.S.
DCEG scientists are spearheading the Premature Mortality Project—an interdisciplinary, multi-institutional effort to characterize U.S. trends in premature mortality. In the process, the team has uncovered distinct mortality trends by race, ethnicity, age, and region, and provided crucial information about the ongoing, well-publicized, drug overdose epidemic.
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Of Microbes and Men: Advancing Epidemiologic Research on the Human Microbiome
DCEG investigators have developed a program to advance epidemiologic research on the microbiome.
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Cari Kitahara Explores Medical Radiation Exposures and Thyroid Cancer Etiology
Dr. Cari Kitahara has built a multidisciplinary research program to explore cancer risks from occupational and medical radiation exposures, and to investigate the etiology of radiosensitive tumors, including thyroid cancer.