DCEG researchers conduct studies on cancers of the endometrium and uterus, known as endometrial and uterine cancer. Endometrial cancer forms in the tissue lining the uterus, and most endometrial cancers are adenocarcinomas. Selected studies include:
A feasibility study to assess the use of alternative sampling techniques and molecular assays to detect endometrial and ovarian cancer
A study to investigate the association of risk factors with molecular changes in the ovaries and endometrium
A retrospective cohort study that uses data from the FIT clinical trial to evaluate how bone mineral density of the hip is related to subsequent cancer risk; including a nested case-cohort study of circulating sex steroid hormones in relation to breast, endometrial, ovarian, and colorectal cancer risk
Retrospective cohort studies of women treated for infertility with ovulation-stimulating drugs to evaluate risk of breast and gynecologic cancers
A study of common inherited variation associated with risk of ovarian cancer, carried out using data and biospeciments from a population-based case-control study of ovarian and endometrial cancer conducted among female residents of Warsaw and Lodz (Poland).
A nested case-control study of endometrial and ovarian cancers assessing the roles of estrogens, estrogen metabolites, androgens, and androgen metabolites in the etiologies of these cancers
A case-control study nested within a retrospective cohort of women diagnosed with endometrial hyperplasia
A prospective study of women who are at increased risk of ovarian cancer either because they or a close relative carry a cancer-causing variation in the BRCA1 or BRCA2 genes, or because they have a strong family history of breast and/or ovarian cancer. This study is closed to patient enrollment but data analysis is ongoing.