Active Clinical Studies
A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two types of clinical studies: clinical trials and observational studies.
DCEG carries out observational studies mostly in families with a known or suspected cancer predisposition syndrome, or families that have a higher-than-expected rate of cancer. In an observational study, investigators assess health outcomes in groups of participants according to a protocol or research plan. Individuals and families agree to share information about their medical history and other information in order to expand our understanding of how cancer aggregates in families. Although some participants are seen at the NIH Clinical Center, DCEG clinical studies do not evaluate treatment or other interventions, as in a clinical trial.
Related Content
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Psychosocial Effects of Cancer Predisposition SyndromesStudies to identify best practices to counsel and care for at-risk individuals and families
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Hereditary Syndromes, Public Health Impact of DCEG ResearchPublic Health Impact of Research on Hereditary Syndromes
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Clinical Genetics BranchStudying individuals and populations at high genetic risk of cancer to uncover etiology and advance clinical care
Learn About Active Clinical Studies
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Atypical Spitzoid Tumor Study
A search for novel genes associated with susceptibility to atypical spitzoid tumors.
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DICER1 Natural History Study
An observational study of individuals with DICER1-related tumors and their families
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Familial Blood and Lymph Node Cancers Study
Study of five familial blood and lymph node cancers
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Familial Chronic Lymphocytic Leukemia Study
If CLL runs in your family, NCI invites you and your family to discuss joining our study, in order to help us learn more about this disease
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Familial Chordoma Study
Families with two or more blood relatives with chordoma may be eligible to participate
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Familial Melanoma Study
Studying how genetic and environmental factors contribute to the development of melanoma in families and in the population.
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Inherited Bone Marrow Failure Syndromes (IBMFS)
A study aimed at understanding how cancers develop in persons with inherited bone marrow failure syndromes (IBMFS)
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Li-Fraumeni Syndrome (LFS) Study
Individuals and their family members with known mutations in TP53 or fulfilling the study eligibility criteria may enroll in the study
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RASopathies Study
A clinical study to better understand the development of tumors in patients with a RASopathy.
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Waldenström's Macroglobulinemia Study
A study of Waldenström's Macroglobulinemia (WM), a rare type of tumor that belongs to a group of disorders called lymphoproliferative diseases