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Discovering the causes of cancer and the means of prevention

Thyroid Cancer Risk Assessment Tool (tcrat)

The R package thyroid implements a risk prediction model developed by NCI researchers to calculate the absolute risk of developing a second primary thyroid cancer (SPTC) in individuals who were diagnosed with a cancer during their childhood.


  • Kovalchik SA, Ronckers CM, Veiga LHS et al. Absolute risk prediction of second primary thyroid cancer among five-year survivors of childhood cancer. Journal of Clinical Oncology 2012