DCEG News Updates
The latest news and research findings from the Division of Cancer Epidemiology and Genetics.
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Physical Activity, Metabolic Adaptation, and Risk of Breast Cancer
A new study by Dr. Eleanor Watts and investigators in the Metabolic Epidemiology Branch explores how physical activity influences metabolic pathways and how these changes might lower breast cancer risk. Higher physical activity was associated with a broad range of metabolic adaptations, highlighting potential role of fatty acid metabolism in breast cancer prevention.
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Mary Ward Retires from the NCI
Dr. Ward retired on October 31, 2024, after 30 years of federal service. She investigated environmental and occupational causes of cancer, with special emphasis on drinking water contaminants, pesticides, and other chemicals in relation to the etiology of childhood leukemia, gastrointestinal cancers, and thyroid cancer.
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Stephen Chanock Elected to the National Academy of Medicine
Dr. Stephen Chanock, director of DCEG, was elected as a member of the National Academy of Medicine on October 21, 2024 during their annual meeting.
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2024 iCURE Scholars Welcomed to NCI and DCEG
Tawnjerae Joe and Douglas Monroe are the 2024 incoming NCI Intramural Continuing Umbrella of Research Experiences (iCURE) Program Scholars.
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2024 NCI Principal Investigators Retreat
The 2024 NCI Principal Investigators Retreat gathered principal investigators from the two intramural divisions of NCI, Division of Cancer Epidemiology & Genetics and the Center for Cancer Research. The retreat was held at Hood College in Frederick, Maryland, on October 15, 2024.
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2025 DCEG Fellows' Awards for Research Excellence
The 2025 DCEG Fellows' Award for Research Excellence (DFARE) recognizes the outstanding scientific research performed by DCEG fellows and provides funding for travel to scientific meetings or conferences.
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Rena Jones Awarded Scientific Tenure by the NIH
Dr. Rena Jones was awarded scientific tenure by the NIH and promoted to senior investigator in the Occupational and Environmental Epidemiology Branch in October 2024. She studies the effects of environmental exposures on cancer risk.
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2025 NCI Director’s Intramural Innovation Awards
Tongwu Zhang, Batel Blechter, Thong Luong, and Maya Spaur received 2025 NCI Director’s Intramural Innovation Awards, which support the development of highly innovative approaches and technology aimed at significant cancer–related problems.
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Guidelines for Diagnosis and Management of Pediatric Melanocytic Tumors
A multidisciplinary panel of experts, convened by the Children’s Oncology Group, has published consensus guidelines for diagnostic evaluation and surgical management of pediatric melanocytic tumors.
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2024 Summer Internship Program in DCEG
In the summer of 2024, 30 interns from 11 states and the District of Columbia, came to do research in every branch of DCEG as well as in the Trans-Divisional Research Program.
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Optimizing the Workforce: The Importance of Fellows
Fellows are an integral part of the interdisciplinary teams conducting cutting-edge research in DCEG. Continually recruiting and training talented fellows is vital for optimizing the Division’s workforce. In early 2024, DCEG published four videos outlining some of the Division’s values and the advantages a DCEG fellowship offers, as expressed by fellows, investigators, and Division’s Office of Education staff.
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Single Cell Atlas Characterizes Mechanisms of Lung Cancer Risk Variants
Multiple genetic loci are associated with lung cancer risk, but the underlying genetic mechanisms remain poorly understood. Dr. Jiyeon Choi from the Laboratory of Translational Genomics and her colleagues analyzed normal lung cells from ever- and never-smokers using single-cell multiomics. The data highlighted cell-type-specific gene regulation underlying lung cancer susceptibility.
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Genomic Landscape of Sebaceous Tumors
Dr. Michael Sargen, in collaboration with investigators in the Center for Cancer Research, compared the genomic landscape of benign and malignant sebaceous tumors to identify molecular changes that could potentially be diagnostic biomarkers or targeted for therapy.
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Debra Silverman to Retire from the NCI After Over 50 Years
Dr. Debra Silverman will retire from the NCI after over 50 years of service and 16 years leading the Occupational and Environmental Epidemiology Branch. She dedicated her career to investigating occupational, environmental, and host factors associated with cancers of the bladder, lung, and pancreas. In addition, Dr. Silverman paved the way for other women to enter the field of biostatistics and epidemiology, shepherding junior investigators to leadership roles.
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Mark Purdue Appointed Director of Occupational and Environmental Epidemiology Branch
Dr. Purdue is an internationally recognized expert in the study of cancer associations with occupational and environmental exposures to chlorinated solvents, per- and polyfluoroalkyl substances (PFAS) and other agents, and the etiology of kidney cancer.
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Megan Clarke Departs DCEG
Megan Clarke, former Earl Stadman investigator in the Clinical Genetics Branch, began a new position at the pharmaceutical firm Abbvie in September 2024. During her tenure in DCEG, she combined molecular, clinical, and population-based approaches to address etiology, prevention, and early detection of anogenital and endometrial cancers. Her discoveries advanced understanding of natural history, influenced clinical management guidelines, and address cancer disparities.
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Research on Long Term Impacts of Proton and Photon Therapy Featured in NIH Intramural Blog
NIH Intramural Research Program highlights Dr. Kitahara's research on the impact of photon and proton therapies among childhood cancer survivors and their risk of second cancer.
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Somatic Mutations in Routinely Collected Cervical Cells Associated with Infection Outcome and HPV Type
Investigators in the Clinical Genetics Branch, led by senior investigator Lisa Mirabello and former research fellow Maísa Pinheiro, used deep targeted sequencing to look for hotspot somatic driver mutations resulting from persistent infection with one of the three most carcinogenic types of human papillomavirus (HPV types 16, 18, and 45) in cells collected during routine screening for cervical cancer. These mutations may serve as a clinically meaningful biomarker of carcinogenesis in individuals with persistent HPV infection.
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NIH Fellows’ Award for Research Excellence Winners
Ten DCEG fellows won the NIH Fellows’ Award for Research Excellence (FARE), which recognizes outstanding scientific research performed by NIH intramural postdoctoral fellows.
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Danping Liu Awarded Scientific Tenure by the NIH
In August 2024, Dr. Danping Liu was awarded scientific tenure by the NIH and promoted to senior investigator in the Biostatistics Branch. Dr. Liu is recognized for his expertise in longitudinal data methodology, risk prediction modeling, biomarker data analyses, missing data methods, and cancer registry linkage.