The Kenya Breast Cancer Study utilizes molecular and genomic approaches to study breast tumors and tumor microenvironment (TME), among African women. This study aims to improve understanding of distinct tumor biology related to breast cancer risk factors and corresponding clinical outcomes in this population.
DCEG researchers will analyze gene expression profiles in tumor tissue to characterize intrinsic and immune subtypes, and tumor microenvironment (TME). Investigators will also analyze tumor and paired normal DNA using a targeted DNA sequencing panel that includes known breast cancer driver genes and will associate genomic alterations with etiologic factors.
This study will leverage publicly available data and those collected through collaborative studies for genomic comparisons in different populations, including researcher efforts at the Aga Khan University Hospital in Nairobi (AKUHN).
For more information, contact Rose Yang.
Integrative Tumor Epidemiology Branch – Research Areas