Golestan Cohort Study

photograph of a cooking stove with smoke from burning wood

Novel Risk Factors for Esophageal Cancer

Biomarkers of exposure to combustion by-products show role of PAHs and VOCs.

The Golestan Cohort Study evaluates the environmental and genetic risk factors for esophageal squamous cell carcinoma (ESCC) in Golestan Province, Iran.

The study is led by the Digestive Disease Research Center of Tehran University of Medical Sciences in collaboration with DCEG and the International Agency for Research on Cancer in Lyon. From 2004 – 2008, the study recruited approximately 50,000 adults.

Baseline assessments included a lifestyle questionnaire, a semi-quantitative food frequency questionnaire, and collections of blood, hair, nails, and urine. Measurements included height, weight, waist and hip circumference, body size at different ages, and physical activity. Annual follow-up is ongoing.

For more information, contact Christian Abnet.

Metabolic Epidemiology Branch - Research Areas

Access GEMShare

Questionnaire data and biospecimens from the Golestan Cohort Study are available upon request to outside researchers. Submit proposals through the GEMINI Shared Repository (GEMShare).