This hospital-based case-control study was conducted from 1999 to 2003 in collaboration with the International Agency for Research on Cancer to evaluate kidney cancer risks in relation to occupational and other environmental and lifestyle exposures in six centers across Eastern Europe (Moscow, Russia; Brno, Prague, and Central Moravia, Czech Republic; Lodz, Poland; Bucharest, Romania). Strengths of this study include its large sample size (1,100 cases and 1,500 controls), detailed occupational exposure assessment, collection of pre-treatment blood and frozen tumor tissue specimens, and case survival follow-up. Factors being evaluated include occupational exposures, lifestyle factors, medical conditions, markers of genetic susceptibility and tumor molecular characteristics.
For more information, contact Dr. Mark Purdue.
Occupational and Environmental Epidemiology Branch - Research Areas